Powered by nature and proven by science, Lean Leaf™ promotes healthy weight loss through natural thermogenesis, improved metabolism, and appetite control. Every ingredient is carefully chosen from plant-based sources and supported by peer-reviewed trials and extensive clinical research, giving you confidence in both its safety and effectiveness. With consistent use, Lean Leaf™ helps you burn fat, increase energy, and maintain long-term results the natural way.
Other Ingredients: Vegetable Cellulose (Veggie Capsule)
Take two Lean Leaf™ capsules daily with water, ideally 20–30 minutes before a meal to maximize thermogenic support. For best results, use consistently as part of your daily routine, paired with a balanced diet and regular physical activity.
Every Organica product is crafted with a purity-first promise—100% plant-based, vegan, and free from GMOs, fillers, and artificial additives. Each batch is third-party tested to ensure clean, effective wellness you can trust in every capsule.
Supports natural calorie-burning through increased body heat and fat-converting energy processes.
Backed by plant-based compounds that help encourage steady, sustainable weight loss over time.
Encourages balanced metabolic activity to help manage weight and sustain energy naturally.
Boosts stamina, mental clarity, and drive without stimulants by revitalizing endocrine and adrenal function.
Helps curb unwanted snacking and late-night cravings by supporting satiety and hunger hormone balance.
Soothes the digestive tract and supports healthy gut rhythm for smoother digestion and nutrient absorption.
Backed by plant-based compounds that help encourage steady, sustainable weight loss over time.
Supports natural calorie-burning through increased body heat and fat-converting energy processes.
Encourages balanced metabolic activity to help manage weight and sustain energy naturally.
Boosts stamina, mental clarity, and drive without stimulants by revitalizing endocrine and adrenal function.
Helps curb unwanted snacking and late-night cravings by supporting satiety and hunger hormone balance.
Soothes the digestive tract and supports healthy gut rhythm for smoother digestion and nutrient absorption.
Green Tea Extract standardized to 50% EGCG for fat burn.
Green Tea (Camellia sinensis) — a catechin-rich leaf extract centered on EGCG that supports natural weight management via thermogenesis/fat-oxidation, body-fat & weight reduction, and exercise fat-burn synergy. For the strongest human data, use standardized extracts (e.g., ≥45–60% catechins or ≥50% EGCG) that retain natural caffeine.
Phytochemical Profile
Recent meta-analyses of randomized trials report reductions in body mass/BMI and body-fat percentage with green tea extract; several also note waist/abdominal fat improvements in at-risk groups.
Study chips: ~500–700 mg catechins/day (≈300–450 mg EGCG) • 8–12 wk • Endpoints: body mass, BMI, body-fat %, waist/abdominal fat.
Systematic reviews (2018–2023) show supportive shifts in respiratory quotient (toward fat use) and small increases in resting energy expenditure in many studies (some neutral)—overall signal favors fat oxidation when catechins are paired with natural caffeine.
Study chips: EGCG 100–800 mg/day, acute and 8–12 wk trials • Endpoints: RMR/24-h EE, respiratory quotient.
Human trials demonstrate higher fat oxidation during moderate exercise after green tea/matcha intake, and newer reviews suggest additive effects when green tea is combined with aerobic or resistance training programs.
Study chips: Single pre-exercise dose (60–90 min prior) or daily use with training • Endpoints: exercise fat-oxidation (RER/RQ), body-comp change over weeks.
https://www.cambridge.org/core/journals/british-journal-of-nutrition
https://www.mdpi.com/journal/nutrients
https://journals.humankinetics.com/journal/ijsnem
https://onlinelibrary.wiley.com/journal/1467789x
https://www.tandfonline.com/toc/uacn20/current
• https://www.sciencedirect.com/journal/clinical-nutrition
Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Individuals sensitive to caffeine or taking medications should consult a clinician before use.
Hot chili pepper extract delivering capsaicinoids for thermogenesis.
Capsaicin (Capsicum spp.) — a pungent capsaicinoid from chili peppers (and its non-pungent analogs, capsinoids) that supports natural weight management via thermogenesis & fat oxidation, body-weight/waist reductions, and appetite/energy-intake control. Best-in-class products use standardized capsaicinoid/capsinoid extracts in capsule or powder formats.
Phytochemical Profile
A 2023 systematic review/meta-analysis of RCTs in overweight/obese adults reports reductions in body mass, BMI, and waist circumference with capsaicin supplementation vs. placebo (effect sizes modest but significant). (Cambridge University Press & Assessment)
Study chips: Daily capsaicinoids/capsinoids; 8–12 wk; endpoints: BW, BMI, WC; designs: DB-RCTs.
A 2020 meta-analysis concludes capsaicinoids/capsinoids increase energy expenditure and fat oxidation in adults; 2019–2020 work also links these effects to TRPV1-mediated BAT activation/vascular changes in humans. (ResearchGate, Oxford Academic, MDPI)
Study chips: Acute and multi-week dosing; endpoints: EE, RMR/REE, RQ/RER, BAT activity; designs: DB-RCTs/crossover.
Recent reviews (2019–2022) synthesize human trials showing lower ad libitum energy intake and higher satiety after capsaicinoids/capsinoids, supporting adherence to calorie-deficit programs. (Individual trial results vary by dose and pungency.) (ScienceDirect)
Study chips: Pre-meal or daily dosing; endpoints: energy-intake (kcal), appetite ratings; designs: controlled meals, DB-RCTs.
https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/AF1C3A4331A35BA12CE925B0B56818B8
https://doi.org/10.1002/ptr.6897
https://doi.org/10.1093/advances/nmy067
https://www.mdpi.com/2072-6643/12/9/2676
https://www.sciencedirect.com/science/article/pii/S2666149722000196
Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. People sensitive to spicy compounds, those with GI conditions, or taking certain medications should consult a clinician before use.
Clinically studied to help curb snacking.
Saffron (Crocus sativus) — standardized stigma extract that supports natural weight goals through appetite/craving control, body-weight/waist reductions, and diet-adherence via mood support. Modern extracts declare crocins/crocetin & safranal on the COA; common clinical dosing is ~28–30 mg/day (often 14 mg twice daily).
Phytochemical Profile
Recent randomized, placebo-controlled trials with standardized saffron report lower hunger/craving scores, less between-meal snacking, and reduced ad libitum energy intake—a key driver of weight change.
Study chips: ~28–30 mg/day; 8–12 wk; endpoints: appetite/craving VAS, snack frequency, kcal intake; designs: DB-RCTs.
Meta-analyses and RCTs since 2018 indicate small, favorable reductions in body weight/BMI and waist circumference in overweight adults using saffron/crocin, especially when paired with diet or activity programs.
Study chips: saffron extract or crocin; 8–12 wk; endpoints: BW, BMI, WC; designs: DB-RCTs; pooled analyses.
Multiple 2018–2024 saffron RCTs show improved mood and reduced stress/anxiety, which in weight-management settings correlates with fewer episodes of emotional eating and better plan adherence.
Study chips: ~28–30 mg/day; 8–12 wk; endpoints: mood scales (e.g., DASS/PHQ), emotional-eating indices; designs: DB-RCTs.
https://www.mdpi.com/journal/nutrients
https://onlinelibrary.wiley.com/journal/10991573
https://www.sciencedirect.com/journal/complementary-therapies-in-medicine
https://www.sciencedirect.com/journal/journal-of-affective-disorders
https://www.cambridge.org/core/journals/british-journal-of-nutrition
Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Avoid use during pregnancy; consult a clinician if you use anticoagulants or have bleeding disorders.
Thermogenic spice that supports brown-fat activity.
Grains of Paradise (Aframomum melegueta) — a ginger-family spice standardized for 6-paradol (with 6-gingerol/6-shogaol) that supports natural weight goals via thermogenesis & energy expenditure, visceral-fat/waist reductions, and brown-fat (BAT) recruitment. Best-in-class extracts declare total paradols on the COA (e.g., ≥2–10%) and are non-stimulant.
Phytochemical Profile
A 12-week, double-blind, placebo-controlled RCT in overweight adults (n≈70) using a 6-paradol–standardized extract, 500 mg/day reported a significant increase in resting energy expenditure vs placebo.
Study chips: 500 mg/day; 12 wk; endpoints: indirect calorimetry (EE); design: DB-RCT.
In the same 2022 RCT, visceral fat area (CT) and body weight/BMI fell significantly vs placebo. Complementary human data (2021, JNSV) in adults with low BAT showed recruited thermogenesis and reduced body fat after prolonged intake.
Study chips: 8–12+ wk; endpoints: CT/DEXA visceral fat, BW/BMI; designs: DB-RCT & controlled human trial.
Modern reviews in humans highlight diet-induced BAT activation/recruitment as a viable weight-management target. Grains of Paradise’s TRPV1-active paradols align with this pathway, helping shift fuel use toward fat oxidation and complementing aerobic/resistance training.
Study chips: nutritional BAT activators; endpoints: EE, RQ/RER, BAT activity; designs: human trials & mechanistic reviews.
https://doi.org/10.2147/DDDT.S367350
https://www.jstage.jst.go.jp/article/jnsv/67/2/67_99/_pdf
https://www.e-enm.org/journal/view.php?doi=10.3803/EnM.2023.1659
https://www.sciencedirect.com/science/article/pii/S2161831322003854
https://ajcn.nutrition.org/article/S0002-9165(22)02760-5/fulltext
Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Avoid use if pregnant/nursing; consult a clinician if you have GI conditions or take medications.
Origin: Gurmar (Gymnema sylvestre) — a leaf extract standardized for gymnemic acids that supports weight goals by curbing sugar intake/cravings, reducing ad-libitum calories & waist/weight over weeks, and smoothing post-meal glucose/insulin to prevent rebound hunger. Often delivered as capsules or fast-dissolving lozenges/mints that briefly block sweet taste.
Phytochemical Profile
Double-blind, placebo-controlled human studies using Gymnema lozenges/mints show lower desire for sweet foods and reduced immediate intake of high-sugar snacks vs placebo; repeated use supports better adherence to calorie targets.
Study chips: single dose before dessert or daily for 8–12 wk • Endpoints: craving VAS, hedonic ratings, ad-libitum kcal • Designs: DB-RCTs/crossover.
When paired with diet/exercise, daily Gymnema extract has produced modest, significant reductions in body weight/BMI/waist vs placebo in overweight adults across multi-week trials (effect sizes small but meaningful for adherence-driven loss).
Study chips: ~300–600 mg/day standardized extract or lozenge use • 8–12 wk • Endpoints: BW, BMI, WC, snack frequency • Design: DB-RCTs.
Human trials report lower postprandial glucose/insulin excursions when Gymnema is taken with carbohydrate, helping reduce reactive hunger and late-day snacking—an indirect but practical lever for weight control.
Study chips: extract with/just before carb meals • Endpoints: PPG, insulin AUC, fullness/satiety ratings • Designs: randomized/controlled.
https://www.sciencedirect.com/journal/appetite
https://www.mdpi.com/journal/nutrients
https://onlinelibrary.wiley.com/journal/10991573
https://www.tandfonline.com/toc/ijds20/current
• https://www.sciencedirect.com/journal/complementary-therapies-in-medicine
https://www.frontiersin.org/journals/pharmacology
Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. If you are pregnant/breastfeeding, have diabetes, or use glucose-lowering medications, consult a clinician before use (risk of additive effects).
Origin: Yerba Mate (Ilex paraguariensis) — a South American holly leaf used as a brewed “mate” that supports natural weight goals via thermogenesis & fat oxidation, body-weight/waist reductions, and appetite/glycemic support. Modern extracts standardize chlorogenic acids, xanthines (caffeine/theobromine), and matesaponins for consistent activity.
Phytochemical Profile
Recent human reviews/meta-analyses (2018–2023) summarizing randomized trials report modest but significant improvements in body weight/BMI and central adiposity with daily yerba-mate versus placebo, particularly in overweight adults following diet/activity programs.
Study chips: ~1–3 g/day tea/extract (capsules or beverage) • 8–12 wk • Endpoints: BW, BMI, waist • Design: DB-RCTs; pooled analyses.
Synthesis of 2018+ clinical data shows increases in energy expenditure and greater fat oxidation at rest and during submaximal exercise after yerba-mate ingestion—an effect attributed to chlorogenic acids + xanthines synergy.
Study chips: single dose and multi-week use • Endpoints: RMR/REE, RQ/RER, exercise fat-oxidation • Design: DB-RCTs/crossover; mixed but supportive overall.
Controlled trials and 2019–2023 reviews indicate lower ad-libitum calorie intake and smoother post-prandial glucose/insulin with yerba-mate or chlorogenic-acid–rich mate extracts, aiding adherence to a calorie deficit.
Study chips: pre-meal dosing or daily intake • Endpoints: kcal intake, appetite VAS, PPG/insulin AUC • Design: randomized/controlled.
https://www.mdpi.com/journal/nutrients
https://onlinelibrary.wiley.com/journal/10991573
https://www.cambridge.org/core/journals/british-journal-of-nutrition
• https://www.sciencedirect.com/journal/clinical-nutrition
https://journals.humankinetics.com/journal/ijsnem
https://academic.oup.com/advances
Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Individuals sensitive to caffeine or on medications should consult a clinician before use.
Origin: Ginger Root (Zingiber officinale) is a culinary rhizome long used in Ayurveda and East–Asian medicine for digestion and comfort. Modern supplements use powders and standardized extracts (often declared for gingerols/shogaols, e.g., ≥5% gingerols) in capsules, chews, and drink blends.
How it works
Key pungent compounds—6-gingerol and 6-shogaol—modulate NF-κB/COX-2/LOX inflammatory signaling and activate Nrf2/HO-1 antioxidant defenses. Ginger also engages TRPV1/TRPA1 channels and shows 5-HT3–antagonist and prokinetic actions in the gut—mechanisms consistent with inflammation relief, digestive comfort, antioxidant capacity, anti-nausea, and glycemic support.
1) Inflammation & Joint Comfort
Meta-analyses of randomized trials (knee OA) show reduced pain and better function with oral ginger vs placebo, with fewer adverse events than NSAIDs in head-to-head data.
Study chips: Dose 500–1,000 mg/day extract (or 1–3 g/day powder) • Duration 8–12 wk • Endpoints WOMAC/KOOS, VAS • Design DB-RCTs + meta-analyses.
2) Digestion (Functional Dyspepsia/Gastric Emptying)
Controlled human studies report faster gastric emptying and improved dyspepsia symptoms with ginger; its prokinetic and 5-HT3 actions align with smoother post-meal comfort.
Study chips: Dose 1–1.5 g/day powder or standardized extract • Duration 2–8 wk • Endpoints gastric emptying, symptom scores • Design DB-RCTs/crossover.
3) Appetite & Thermogenesis (acute → short-term)
Controlled human studies since 2018 show higher fullness/lower hunger ratings, reduced ad-libitum intake, and supportive shifts in energy expenditure/fat use (findings vary by dose/form).
Study chips: single pre-meal dose or daily use • Endpoints: appetite VAS, kcal intake, RER/RQ, TEF/RMR • Design: crossover/DB-RCTs.
4) Appetite & Thermogenesis (acute → short-term)
Controlled human studies since 2018 show higher fullness/lower hunger ratings, reduced ad-libitum intake, and supportive shifts in energy expenditure/fat use (findings vary by dose/form).
Study chips: single pre-meal dose or daily use • Endpoints: appetite VAS, kcal intake, RER/RQ, TEF/RMR • Design: crossover/DB-RCTs.
5) Glycemic Support (T2D/Metabolic)
Meta-analyses of RCTs in type-2 diabetes report reductions in fasting glucose and HbA1c, with improvements in some inflammatory markers.
Study chips: Dose 1–3 g/day • Duration 8–12 wk • Endpoints FBG, HbA1c, CRP • Design DB-RCTs; meta-analyses.
Summary
Human randomized trials indicate that standardized ginger can reduce inflammatory discomfort (especially knee OA), improve digestive comfort and gastric kinetics, raise antioxidant capacity, ease nausea, and support glucose control in at-risk groups. For best translation, use clearly standardized extracts (gingerols/shogaols) or clinically aligned powders, taken daily for 4–12 weeks at studied doses.
Why choose Organica
References
https://www.sciencedirect.com/journal/osteoarthritis-and-cartilage
https://arthritis-research.biomedcentral.com/
https://journals.lww.com/eurojgh/pages/default.aspx
https://bmccomplementmedtherapies.biomedcentral.com/
https://onlinelibrary.wiley.com/journal/10991573
https://www.sciencedirect.com/journal/nutrition
Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a clinician if pregnant/nursing, before surgery, or if you use anticoagulants or have gallstones/biliary concerns.
Origin: Gurmar (Gymnema sylvestre) — a leaf extract standardized for gymnemic acids that supports weight goals by curbing sugar intake/cravings, reducing ad-libitum calories & waist/weight over weeks, and smoothing post-meal glucose/insulin to prevent rebound hunger. Often delivered as capsules or fast-dissolving lozenges/mints that briefly block sweet taste.
Phytochemical Profile
Double-blind, placebo-controlled human studies using Gymnema lozenges/mints show lower desire for sweet foods and reduced immediate intake of high-sugar snacks vs placebo; repeated use supports better adherence to calorie targets.
Study chips: single dose before dessert or daily for 8–12 wk • Endpoints: craving VAS, hedonic ratings, ad-libitum kcal • Designs: DB-RCTs/crossover.
When paired with diet/exercise, daily Gymnema extract has produced modest, significant reductions in body weight/BMI/waist vs placebo in overweight adults across multi-week trials (effect sizes small but meaningful for adherence-driven loss).
Study chips: ~300–600 mg/day standardized extract or lozenge use • 8–12 wk • Endpoints: BW, BMI, WC, snack frequency • Design: DB-RCTs.
Human trials report lower postprandial glucose/insulin excursions when Gymnema is taken with carbohydrate, helping reduce reactive hunger and late-day snacking—an indirect but practical lever for weight control.
Study chips: extract with/just before carb meals • Endpoints: PPG, insulin AUC, fullness/satiety ratings • Designs: randomized/controlled.
https://www.sciencedirect.com/journal/appetite
https://www.mdpi.com/journal/nutrients
https://onlinelibrary.wiley.com/journal/10991573
https://www.tandfonline.com/toc/ijds20/current
• https://www.sciencedirect.com/journal/complementary-therapies-in-medicine
https://www.frontiersin.org/journals/pharmacology
Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. If you are pregnant/breastfeeding, have diabetes, or use glucose-lowering medications, consult a clinician before use (risk of additive effects).
Origin: Yerba Mate (Ilex paraguariensis) — a South American holly leaf used as a brewed “mate” that supports natural weight goals via thermogenesis & fat oxidation, body-weight/waist reductions, and appetite/glycemic support. Modern extracts standardize chlorogenic acids, xanthines (caffeine/theobromine), and matesaponins for consistent activity.
Phytochemical Profile
Recent human reviews/meta-analyses (2018–2023) summarizing randomized trials report modest but significant improvements in body weight/BMI and central adiposity with daily yerba-mate versus placebo, particularly in overweight adults following diet/activity programs.
Study chips: ~1–3 g/day tea/extract (capsules or beverage) • 8–12 wk • Endpoints: BW, BMI, waist • Design: DB-RCTs; pooled analyses.
Synthesis of 2018+ clinical data shows increases in energy expenditure and greater fat oxidation at rest and during submaximal exercise after yerba-mate ingestion—an effect attributed to chlorogenic acids + xanthines synergy.
Study chips: single dose and multi-week use • Endpoints: RMR/REE, RQ/RER, exercise fat-oxidation • Design: DB-RCTs/crossover; mixed but supportive overall.
Controlled trials and 2019–2023 reviews indicate lower ad-libitum calorie intake and smoother post-prandial glucose/insulin with yerba-mate or chlorogenic-acid–rich mate extracts, aiding adherence to a calorie deficit.
Study chips: pre-meal dosing or daily intake • Endpoints: kcal intake, appetite VAS, PPG/insulin AUC • Design: randomized/controlled.
https://www.mdpi.com/journal/nutrients
https://onlinelibrary.wiley.com/journal/10991573
https://www.cambridge.org/core/journals/british-journal-of-nutrition
• https://www.sciencedirect.com/journal/clinical-nutrition
https://journals.humankinetics.com/journal/ijsnem
https://academic.oup.com/advances
Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Individuals sensitive to caffeine or on medications should consult a clinician before use.
Saffron (Crocus sativus) — standardized stigma extract that supports natural weight goals through appetite/craving control, body-weight/waist reductions, and diet-adherence via mood support. Modern extracts declare crocins/crocetin & safranal on the COA; common clinical dosing is ~28–30 mg/day (often 14 mg twice daily).
Phytochemical Profile
Recent randomized, placebo-controlled trials with standardized saffron report lower hunger/craving scores, less between-meal snacking, and reduced ad libitum energy intake—a key driver of weight change.
Study chips: ~28–30 mg/day; 8–12 wk; endpoints: appetite/craving VAS, snack frequency, kcal intake; designs: DB-RCTs.
Meta-analyses and RCTs since 2018 indicate small, favorable reductions in body weight/BMI and waist circumference in overweight adults using saffron/crocin, especially when paired with diet or activity programs.
Study chips: saffron extract or crocin; 8–12 wk; endpoints: BW, BMI, WC; designs: DB-RCTs; pooled analyses.
Multiple 2018–2024 saffron RCTs show improved mood and reduced stress/anxiety, which in weight-management settings correlates with fewer episodes of emotional eating and better plan adherence.
Study chips: ~28–30 mg/day; 8–12 wk; endpoints: mood scales (e.g., DASS/PHQ), emotional-eating indices; designs: DB-RCTs.
https://www.mdpi.com/journal/nutrients
https://onlinelibrary.wiley.com/journal/10991573
https://www.sciencedirect.com/journal/complementary-therapies-in-medicine
https://www.sciencedirect.com/journal/journal-of-affective-disorders
https://www.cambridge.org/core/journals/british-journal-of-nutrition
Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Avoid use during pregnancy; consult a clinician if you use anticoagulants or have bleeding disorders.
Grains of Paradise (Aframomum melegueta) — a ginger-family spice standardized for 6-paradol (with 6-gingerol/6-shogaol) that supports natural weight goals via thermogenesis & energy expenditure, visceral-fat/waist reductions, and brown-fat (BAT) recruitment. Best-in-class extracts declare total paradols on the COA (e.g., ≥2–10%) and are non-stimulant.
Phytochemical Profile
A 12-week, double-blind, placebo-controlled RCT in overweight adults (n≈70) using a 6-paradol–standardized extract, 500 mg/day reported a significant increase in resting energy expenditure vs placebo.
Study chips: 500 mg/day; 12 wk; endpoints: indirect calorimetry (EE); design: DB-RCT.
In the same 2022 RCT, visceral fat area (CT) and body weight/BMI fell significantly vs placebo. Complementary human data (2021, JNSV) in adults with low BAT showed recruited thermogenesis and reduced body fat after prolonged intake.
Study chips: 8–12+ wk; endpoints: CT/DEXA visceral fat, BW/BMI; designs: DB-RCT & controlled human trial.
Modern reviews in humans highlight diet-induced BAT activation/recruitment as a viable weight-management target. Grains of Paradise’s TRPV1-active paradols align with this pathway, helping shift fuel use toward fat oxidation and complementing aerobic/resistance training.
Study chips: nutritional BAT activators; endpoints: EE, RQ/RER, BAT activity; designs: human trials & mechanistic reviews.
https://doi.org/10.2147/DDDT.S367350
https://www.jstage.jst.go.jp/article/jnsv/67/2/67_99/_pdf
https://www.e-enm.org/journal/view.php?doi=10.3803/EnM.2023.1659
https://www.sciencedirect.com/science/article/pii/S2161831322003854
https://ajcn.nutrition.org/article/S0002-9165(22)02760-5/fulltext
Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Avoid use if pregnant/nursing; consult a clinician if you have GI conditions or take medications.
Capsaicin (Capsicum spp.) — a pungent capsaicinoid from chili peppers (and its non-pungent analogs, capsinoids) that supports natural weight management via thermogenesis & fat oxidation, body-weight/waist reductions, and appetite/energy-intake control. Best-in-class products use standardized capsaicinoid/capsinoid extracts in capsule or powder formats.
Phytochemical Profile
A 2023 systematic review/meta-analysis of RCTs in overweight/obese adults reports reductions in body mass, BMI, and waist circumference with capsaicin supplementation vs. placebo (effect sizes modest but significant). (Cambridge University Press & Assessment)
Study chips: Daily capsaicinoids/capsinoids; 8–12 wk; endpoints: BW, BMI, WC; designs: DB-RCTs.
A 2020 meta-analysis concludes capsaicinoids/capsinoids increase energy expenditure and fat oxidation in adults; 2019–2020 work also links these effects to TRPV1-mediated BAT activation/vascular changes in humans. (ResearchGate, Oxford Academic, MDPI)
Study chips: Acute and multi-week dosing; endpoints: EE, RMR/REE, RQ/RER, BAT activity; designs: DB-RCTs/crossover.
Recent reviews (2019–2022) synthesize human trials showing lower ad libitum energy intake and higher satiety after capsaicinoids/capsinoids, supporting adherence to calorie-deficit programs. (Individual trial results vary by dose and pungency.) (ScienceDirect)
Study chips: Pre-meal or daily dosing; endpoints: energy-intake (kcal), appetite ratings; designs: controlled meals, DB-RCTs.
https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/AF1C3A4331A35BA12CE925B0B56818B8
https://doi.org/10.1002/ptr.6897
https://doi.org/10.1093/advances/nmy067
https://www.mdpi.com/2072-6643/12/9/2676
https://www.sciencedirect.com/science/article/pii/S2666149722000196
Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. People sensitive to spicy compounds, those with GI conditions, or taking certain medications should consult a clinician before use.
Origin: Ginger Root (Zingiber officinale) is a culinary rhizome long used in Ayurveda and East–Asian medicine for digestion and comfort. Modern supplements use powders and standardized extracts (often declared for gingerols/shogaols, e.g., ≥5% gingerols) in capsules, chews, and drink blends.
How it works
Key pungent compounds—6-gingerol and 6-shogaol—modulate NF-κB/COX-2/LOX inflammatory signaling and activate Nrf2/HO-1 antioxidant defenses. Ginger also engages TRPV1/TRPA1 channels and shows 5-HT3–antagonist and prokinetic actions in the gut—mechanisms consistent with inflammation relief, digestive comfort, antioxidant capacity, anti-nausea, and glycemic support.
1) Inflammation & Joint Comfort
Meta-analyses of randomized trials (knee OA) show reduced pain and better function with oral ginger vs placebo, with fewer adverse events than NSAIDs in head-to-head data.
Study chips: Dose 500–1,000 mg/day extract (or 1–3 g/day powder) • Duration 8–12 wk • Endpoints WOMAC/KOOS, VAS • Design DB-RCTs + meta-analyses.
2) Digestion (Functional Dyspepsia/Gastric Emptying)
Controlled human studies report faster gastric emptying and improved dyspepsia symptoms with ginger; its prokinetic and 5-HT3 actions align with smoother post-meal comfort.
Study chips: Dose 1–1.5 g/day powder or standardized extract • Duration 2–8 wk • Endpoints gastric emptying, symptom scores • Design DB-RCTs/crossover.
3) Appetite & Thermogenesis (acute → short-term)
Controlled human studies since 2018 show higher fullness/lower hunger ratings, reduced ad-libitum intake, and supportive shifts in energy expenditure/fat use (findings vary by dose/form).
Study chips: single pre-meal dose or daily use • Endpoints: appetite VAS, kcal intake, RER/RQ, TEF/RMR • Design: crossover/DB-RCTs.
4) Appetite & Thermogenesis (acute → short-term)
Controlled human studies since 2018 show higher fullness/lower hunger ratings, reduced ad-libitum intake, and supportive shifts in energy expenditure/fat use (findings vary by dose/form).
Study chips: single pre-meal dose or daily use • Endpoints: appetite VAS, kcal intake, RER/RQ, TEF/RMR • Design: crossover/DB-RCTs.
5) Glycemic Support (T2D/Metabolic)
Meta-analyses of RCTs in type-2 diabetes report reductions in fasting glucose and HbA1c, with improvements in some inflammatory markers.
Study chips: Dose 1–3 g/day • Duration 8–12 wk • Endpoints FBG, HbA1c, CRP • Design DB-RCTs; meta-analyses.
Summary
Human randomized trials indicate that standardized ginger can reduce inflammatory discomfort (especially knee OA), improve digestive comfort and gastric kinetics, raise antioxidant capacity, ease nausea, and support glucose control in at-risk groups. For best translation, use clearly standardized extracts (gingerols/shogaols) or clinically aligned powders, taken daily for 4–12 weeks at studied doses.
Why choose Organica
References
https://www.sciencedirect.com/journal/osteoarthritis-and-cartilage
https://arthritis-research.biomedcentral.com/
https://journals.lww.com/eurojgh/pages/default.aspx
https://bmccomplementmedtherapies.biomedcentral.com/
https://onlinelibrary.wiley.com/journal/10991573
https://www.sciencedirect.com/journal/nutrition
Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a clinician if pregnant/nursing, before surgery, or if you use anticoagulants or have gallstones/biliary concerns.
Green Tea (Camellia sinensis) — a catechin-rich leaf extract centered on EGCG that supports natural weight management via thermogenesis/fat-oxidation, body-fat & weight reduction, and exercise fat-burn synergy. For the strongest human data, use standardized extracts (e.g., ≥45–60% catechins or ≥50% EGCG) that retain natural caffeine.
Phytochemical Profile
Recent meta-analyses of randomized trials report reductions in body mass/BMI and body-fat percentage with green tea extract; several also note waist/abdominal fat improvements in at-risk groups.
Study chips: ~500–700 mg catechins/day (≈300–450 mg EGCG) • 8–12 wk • Endpoints: body mass, BMI, body-fat %, waist/abdominal fat.
Systematic reviews (2018–2023) show supportive shifts in respiratory quotient (toward fat use) and small increases in resting energy expenditure in many studies (some neutral)—overall signal favors fat oxidation when catechins are paired with natural caffeine.
Study chips: EGCG 100–800 mg/day, acute and 8–12 wk trials • Endpoints: RMR/24-h EE, respiratory quotient.
Human trials demonstrate higher fat oxidation during moderate exercise after green tea/matcha intake, and newer reviews suggest additive effects when green tea is combined with aerobic or resistance training programs.
Study chips: Single pre-exercise dose (60–90 min prior) or daily use with training • Endpoints: exercise fat-oxidation (RER/RQ), body-comp change over weeks.
https://www.cambridge.org/core/journals/british-journal-of-nutrition
https://www.mdpi.com/journal/nutrients
https://journals.humankinetics.com/journal/ijsnem
https://onlinelibrary.wiley.com/journal/1467789x
https://www.tandfonline.com/toc/uacn20/current
• https://www.sciencedirect.com/journal/clinical-nutrition
Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Individuals sensitive to caffeine or taking medications should consult a clinician before use.
Natural Botanicals – Real plant extracts you can pronounce; no harmful ingredients or chemicals
Natural Botanicals – Real plant extracts you can pronounce; no harmful ingredients or chemicals
Multi-Angle Formulation - Cohesively crafted to deliver results from 6 different angles
Multi-Angle Formulation - Cohesively crafted to deliver results from 6 different angles
Proven Real Trials – Backed by extensive peer testing for effective, consistent results
Proven Real Trials – Backed by extensive peer testing for effective, consistent results
Clinically Researched – Backed by rigorous clinical data using only proven ingredients
Clinically Researched – Backed by rigorous clinical data using only proven ingredients
Optimal Bioavailability – Absorption-focused design for reliable uptake and persitant results
Optimal Bioavailability – Absorption-focused design for reliable uptake and persitant results
Ethical Sourcing – Supports small family farms, no industrial or exploitative suppliers
Ethical Sourcing – Supports small family farms, no industrial or exploitative suppliers
Glass & Bamboo Packaging – Eco-friendly packaging that protects purity, no harmful plastics
Glass & Bamboo Packaging – Eco-friendly packaging that protects purity, no harmful plastics
QR Code Verified – Scan to see your batch’s lab report and source trail, no hidden supply chains
QR Code Verified – Scan to see your batch’s lab report and source trail, no hidden supply chains
No Fillers or Additives - Clean formulation without fillers, artificial flavors, or harsh preservatives
No Fillers or Additives - Clean formulation without fillers, artificial flavors, or harsh preservatives
Vegan & Allergen-Free – No animal products, dairy, soy, gluten, or common allergens
Vegan & Allergen-Free – No animal products, dairy, soy, gluten, or common allergens
Lean Leaf™ is a targeted weight management formula designed to help you shed excess pounds by combining clinically supported botanical extracts that work synergistically to curb cravings, support fat breakdown, and trigger thermogenesis. With consistent use alongside a healthy diet and exercise, many users experience gradual, sustainable weight loss over 8–12 weeks.
For optimal absorption and effect, take two Lean Leaf™ capsules daily: one 30 minutes before breakfast and one 30 minutes before lunch, each with at least 8 ounces of water. Consistent timing around meals helps manage hunger and maintain steady energy levels throughout the day.
Lean Leaf™ is generally well-tolerated at the recommended dosage. Mild caffeine-related effects (e.g., jitteriness or insomnia) may occur if taken too late in the day. Avoid use if you are pregnant, nursing, have a thyroid disorder, or are sensitive to stimulants. Always consult your healthcare provider before beginning any new supplement regimen.
Lean Leaf™ is generally well-tolerated at the recommended dosage. Mild caffeine-related effects (e.g., jitteriness or insomnia) may occur if taken too late in the day. Avoid use if you are pregnant, nursing, have a thyroid disorder, or are sensitive to stimulants. Always consult your healthcare provider before beginning any new supplement regimen.
You can safely use Lean Leaf™ alongside multivitamins, protein powders, and most herbal supplements. However, avoid stacking with additional high-caffeine products. If you take prescription medications—especially blood thinners, blood pressure drugs, or thyroid medications—consult your doctor to rule out interactions.
While Lean Leaf™ supports weight loss mechanisms, it’s most effective when paired with a calorie-controlled diet and regular physical activity. Think of Lean Leaf™ as a performance boost for your healthy lifestyle, not a replacement for smart eating and exercise.