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Immune Armor™

A powerful immune support formula featuring Reishi, Turkey Tail, elderberry, and antioxidants to build natural defense and promote year-round resilience.
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Antioxidant
Antioxidant Power
Balance
Immune Balance
Immunity
Strengthens Immunity
Inflammation
Reduces Inflammation
Recovery
Accelerates Recovery
Resilience
Boosts Resilience
Immunity
Strengthens Immunity
Antioxidant
Antioxidant Power
Balance
Immune Balance
Inflammation
Reduces Inflammation
Recovery
Accelerates Recovery
Resilience
Boosts Resilience
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Description
Supplement Facts

Supplement Facts

Serving Size: 2 Capsules
Serving Per Container: 60 Capsules
Amount Per Serving
% Daily Value
Quercetin (from Sophora japonic)
250 mg
Andrographis paniculata Extract
200 mg
Larch Arabinogalactan
200 mg
Holy Basil (Tulsi) Leaf Extract
150 mg
Nigella sativa Seed Extract
150 mg
Elderberry Fruit Extract
150 mg
Astragalus Root Extract
150 mg
Bromelain
100 mg
Pelargonium sidoides Root Extract
60 mg
† Daily Value not established

Other Ingredients: Vegetable Cellulose (Veggie Capsule)

How To Use
Purity Promise

Every Organica product is crafted with a purity-first promise—100% plant-based, vegan, and free from GMOs, fillers, and artificial additives. Each batch is third-party tested to ensure clean, effective wellness you can trust in every capsule.

Ingredient Integrity
100% Vegan
Plant-Based
Non-GMO 
Gluten-Free
Dairy-Free
Soy-Free
Sugar-Free
Nut-Free
No Artificial Additives
No Artificial Colors
No Artificial Flavors
No Preservatives
No Fillers or Binders
Certified Clean
Third-Party Tested
Licensed & Certified
Eco-Friendly Farmed
Made in the USA
60 Day Money-Back
$50+ Free Shipping
Third-Party Tested
Easy-Cancellation

Built to Shield. Ready to Rise.

Immune Armor™ delivers full-spectrum immune support with antioxidants, adaptogens, and clinically backed nutrients that fortify your defenses, ease inflammation, and help you recover faster—every day.

Accelerates Daily Recovery

Supports faster bounce-back from immune strain, stress, or illness with revitalizing nutrients and herbs.

Boosts Daily Resilience

Supports your body’s natural ability to stay strong, adaptive, and protected against daily immune stressors.

Delivers Antioxidant Power

Neutralizes harmful free radicals to shield immune cells and tissues from oxidative damage.

Maintains Immune Balance

Promotes a well-regulated immune state—neither overactive nor sluggish—through adaptogens and micronutrients.

Reduces Inflammation Naturally

Helps regulate internal systems and supports a calm, steady response to everyday physical demands.

Strengthens Immune Defense

Helps fortify your body’s frontline defenses against seasonal threats and environmental stressors.

Built to Shield. Ready to Rise.

Immune Armor™ delivers full-spectrum immune support with antioxidants, adaptogens, and clinically backed nutrients that fortify your defenses, ease inflammation, and help you recover faster—every day.

Strengthens Immune Defense

Helps fortify your body’s frontline defenses against seasonal threats and environmental stressors.

Accelerates Daily Recovery

Supports faster bounce-back from immune strain, stress, or illness with revitalizing nutrients and herbs.

Boosts Daily Resilience

Supports your body’s natural ability to stay strong, adaptive, and protected against daily immune stressors.

Delivers Antioxidant Power

Neutralizes harmful free radicals to shield immune cells and tissues from oxidative damage.

Maintains Immune Balance

Promotes a well-regulated immune state—neither overactive nor sluggish—through adaptogens and micronutrients.

Reduces Inflammation Naturally

Helps regulate internal systems and supports a calm, steady response to everyday physical demands.

Main Ingredients

Elderberry

Sambucus nigra

Dark-berry anthocyanins that bolster seasonal upper-airway defenses.

Supports healthy immune response
Antioxidant shield for seasonal challenges
Helps maintain throat & sinus comfort

Elderberry

Sambucus nigra

Origin: Elderberry (Sambucus nigra L.) — standardized fruit extract used for immune defense, daily recovery, and antioxidant support, with growing human evidence for shortening upper-respiratory symptom duration and easing severity. Modern products declare total anthocyanins (e.g., ≥15–20%) and use 4–12-week protocols during high-exposure seasons.

Phytochemical Profile

  • Rich in anthocyanins (cyanidin-3-glucoside/sambubioside) plus flavonols and phenolic acids
  • Mechanisms: antiviral adsorption/entry interference (in vitro), antioxidant/Nrf2 support, and immune-modulating cytokine signaling (balanced, context-dependent)
  • Caffeine-free; vegan; quality COAs list % anthocyanins by HPLC/UV-Vis

Top 5 Clinically Supported Benefits

1) Shorter URTI Duration (daily recovery)
A 2019 meta-analysis of randomized, controlled trials found elderberry supplementation significantly reduced the duration of upper-respiratory symptoms compared with control.
Study chips: Typical daily 300–900 mg fruit extract (standardized) • 5–12 days during illness or 4–12 weeks seasonally • Endpoints symptom days/severity • Design DB-RCTs/meta-analysis.

2) Lower Symptom Severity (immune defense you can feel)
Across RCTs included in the 2018–2021 evidence base, elderberry groups showed reduced global symptom scores (nasal congestion, cough, aches) versus placebo—supporting faster daily recovery.
Study chips: Standardized extracts/syrups • 5–10 days during symptomatic periods • Endpoints composite symptom scales, rescue-meds useDB-RCTs.

3) Immune Balance (cytokine modulation)
Human and translational studies report modulation—not overstimulation—of cytokines (e.g., directionally supporting early innate responses while limiting oxidative stress), aligning with immune balance rather than a blunt up-regulation.
Study chips: 2–4 weeks+ • Endpoints select cytokines/chemokines, WBC subsetsRandomized/controlled; small cohorts.

4) Antioxidant Capacity (daily resilience)
Controlled human trials with elderberry beverages/extracts show increases in total antioxidant capacity (TAC) and reductions in oxidative-stress markers, consistent with its dense anthocyanin profile.
Study chips: 1–8 weeks • Endpoints TAC, SOD/GPx, lipid peroxidationRandomized/controlled.

5) Tolerability & Safety Signals
Across RCTs and meta-analyses, standardized elderberry was well tolerated with adverse events comparable to placebo—supporting seasonal, daily use in wellness stacks.
Study chips: Up to 12 weeks • Endpoints AE rates, discontinuationsDB-RCTs/meta-analyses.

Summary — how Elderberry supports your benefits

  • Immune defense & daily recovery: Anthocyanin-rich extracts help shorten URTI duration and ease symptom severity in RCTs.
  • Daily resilience & antioxidant: High polyphenol density raises antioxidant capacity, buffering oxidative drag during high-exposure periods.
  • Immune balance: Evidence points to context-appropriate modulation rather than overstimulation—useful for everyday wellness.

Why choose Organica’s elderberry

  • Clinically aligned standardization: declare % anthocyanins, batch-verified by HPLC/UV-Vis.
  • Clear protocols: daily preventive use during the season, and acute support at first signs (per RCT patterns).
  • Third-party COA: identity, actives, microbes, heavy metals, pesticides, solvents.
  • cGMP, vegan capsules; clean excipients.

References (2018+; URLs shown as text only)

  • Hawkins, J., et al. “The effect of elderberry on upper respiratory symptoms: a meta-analysis of randomized, controlled clinical trials.” Complementary Therapies in Medicine (2019).
    https://www.sciencedirect.com/journal/complementary-therapies-in-medicine
  • Nutrients (2021–2023). Reviews on berry anthocyanins/elderberry for immune and antioxidant support (human-focused updates).
    https://www.mdpi.com/journal/nutrients
  • Advances in Nutrition (2020–2022). Polyphenols and respiratory/immune health overviews including elderberry.
    https://academic.oup.com/advances
  • Phytotherapy Research (2018–2023). Clinical and mechanistic summaries of Sambucus nigra in URTI contexts.
    https://onlinelibrary.wiley.com/journal/10991573
  • Antioxidants (2020–2023). Human trials on anthocyanin-rich beverages and oxidative-stress markers (elderberry subsets).
    https://www.mdpi.com/journal/antioxidants

Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Do not ingest raw or unripe elder parts (cyanogenic glycosides). Standardized extracts are generally well tolerated; discuss with a clinician if pregnant/nursing, immunocompromised, or on anticoagulants.

Quercetin

Sophora japonica

Stabilizes mast cells production and supports sinus comfort.

Supports mast-cell immune stability
Broad antioxidant superfood
Significantly reduces inflammation

Quercetin

Sophora japonica

Origin: Quercetin — standardized flavonol (typically from Sophora japonica) used for immune defense, daily resilience/recovery, antioxidant support, and immune balance/inflammation reduction. Modern supplements use quercetin anhydrous/dihydrate, or enhanced-bioavailability forms (e.g., Quercetin Phytosome/Quercefit®, EMIQ/isoquercitrin) at ~250–500 mg/day (anhydrous equivalents), often paired with bromelain or vitamin C.

Phytochemical Profile

  • Core actions: NF-κB/COX-2 down-shift (inflammation), Nrf2/HO-1 up-shift (antioxidant), mast-cell stabilization (histamine moderation), endothelial/immune signaling balance
  • Forms & absorption: phytosome and glycosylated forms (EMIQ) yield higher plasma levels vs plain quercetin; bromelain may aid uptake
  • Vegan, non-GMO; quality COAs declare ≥95% quercetin (or equivalence for phytosome/EMIQ)

Top 5 Clinically Supported Benefits

1) Inflammation Reduction (CRP, IL-6, TNF-α)
Meta-analyses of randomized trials in adults with metabolic/inflammatory risk show reductions in hs-CRP, IL-6, and TNF-α with quercetin versus placebo—effect sizes modest but significant.
Study chips: 250–1,000 mg/day (or bioavailable equivalents) • 8–12 wk • Endpoints CRP/hs-CRP, IL-6, TNF-α • Design DB-RCTs; pooled analyses.
Benefit tags: immune balance · inflammation reduction

2) Antioxidant Capacity (TAC ↑; oxidative stress ↓)
Human RCTs report higher total antioxidant capacity (TAC) and lower lipid peroxidation (e.g., MDA/TBARS) with quercetin supplementation—consistent with Nrf2/HO-1 activation.
Study chips: 250–500 mg/day4–12 wk • Endpoints TAC, SOD/GPx, MDA/TBARSRandomized/controlled.
Benefit tags: antioxidant · daily resilience

3) Upper-Respiratory Symptom Load (adjunct human signals)
Recent controlled trials (including combination formulas with vitamin C ± bromelain) show reduced URTI symptom days/severity or fewer sick days, while some trials of quercetin alone are neutral—overall signal favors adjunctive use for daily recovery.
Study chips: 500–1,000 mg/day quercetin (or bioavailable equivalent), sometimes with vitamin C/bromelain • 2–12 wk • Endpoints symptom days, composite scores, sick-daysDB-RCTs.
Benefit tags: immune defense · daily recovery

4) Allergy/Upper-Airway Comfort (mast-cell stabilization)
Pilot RCTs and controlled studies report improved nasal/ocular symptom scores in seasonal-allergy contexts with bioavailable quercetin—consistent with histamine moderation and local anti-inflammatory effects.
Study chips: ~250–500 mg/day (bioavailable forms favored) • 2–8 wk • Endpoints TNSS/eye symptom scales, rescue-meds useRandomized/controlled.
Benefit tags: immune balance · daily resilience

5) Cardiometabolic Support (secondary but supportive)
Meta-analyses since 2018 indicate small reductions in SBP/DBP and improved glycemic markers in at-risk adults—reflecting systemic anti-inflammatory/antioxidant effects that underpin everyday immune resilience.
Study chips: 500–1,000 mg/day8–12 wk • Endpoints SBP/DBP, FBG/HbA1cDB-RCTs/meta-analyses.
Benefit tags: inflammation reduction · antioxidant

Summary — how Quercetin supports your benefits

  • Immune balance & inflammation reduction: Down-regulates NF-κB/COX-2 and moderates cytokines (CRP/IL-6/TNF-α), helping the immune system respond without overreacting.
  • Antioxidant daily resilience: Activates Nrf2/HO-1, raising endogenous defenses (TAC, SOD/GPx) and lowering oxidative burden.
  • Immune defense & daily recovery: As a stand-alone or adjunct with vitamin C/bromelain, quercetin shows human signals for lighter, shorter respiratory symptom loads—useful during high-exposure seasons.

Why choose Organica’s quercetin

  • Clinically aligned dosing: 250–500 mg/day (anhydrous equivalent) in 1–2 caps.
  • Enhanced uptake option: Phytosome (Quercetin Phytosome/Quercefit®) or EMIQ for higher plasma exposure at lower mg.
  • Smart pairing: We include bromelain in Immune Armor™ to aid absorption and add upper-airway comfort.
  • Third-party COA: identity, assay (HPLC/UPLC), heavy metals, microbes, pesticides, solvents.
  • cGMP, vegan capsules; clean excipients.

References

  • Phytotherapy Research (2019–2023) — Meta-analyses/RCTs on quercetin and CRP/IL-6/TNF-α; inflammation outcomes.
    https://onlinelibrary.wiley.com/journal/10991573
  • Nutrients (2020–2024) — Reviews on quercetin bioavailability (phytosome/EMIQ), immune modulation, and respiratory wellness.
    https://www.mdpi.com/journal/nutrients
  • Antioxidants (2020–2023) — Human trials: TAC ↑, oxidative stress ↓ with quercetin supplementation.
    https://www.mdpi.com/journal/antioxidants
  • Clinical Nutrition / Nutrition Reviews (2019–2023) — Meta-analyses on blood pressure and glycemic markers with quercetin.
    https://www.sciencedirect.com/journal/clinical-nutritionhttps://academic.oup.com/nutritionreviews
  • Complementary Therapies in Medicine / Evidence-Based CAM (2019–2023) — RCTs of quercetin (± vitamin C/bromelain) on URTI symptom days/severity.
    https://www.sciencedirect.com/journal/complementary-therapies-in-medicinehttps://www.hindawi.com/journals/ecam/

Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Medication cautions: quercetin may affect drug metabolism (e.g., CYP3A4/P-gp); consult a clinician if using anticoagulants, chemotherapy, antibiotics, or other critical meds. Not recommended in pregnancy/nursing without medical guidance.

Arabinogalactan

Larch Arabinogalactan

Prebiotic larch fiber that strengthens mucosal immunity.

Promotes fewer seasonal cold episodes
Boosts mucosal sIgA levels
Prebiotic SCFAs antioxidant resilience

Arabinogalactan

Larch Arabinogalactan

Arabinogalactan (from Larch, Larix spp.) — standardized prebiotic polysaccharide used for immune defense, daily recovery/resilience, immune balance, inflammation reduction, and antioxidant support. Modern products use highly soluble, low-viscosity fibers composed of β-1,3 galactan backbones with arabinosyl side chains; they dissolve clear, are mildly sweet, and are well tolerated.

Phytochemical Profile

  • Branched arabinose–galactose polysaccharides (typically >85% fiber) from larch wood
  • Prebiotic fermentation → SCFAs (butyrate/propionate) that signal via GPR41/43, supporting barrier integrity, immune balance, and oxidative-stress control (Nrf2)
  • Immunology: supports dendritic/NK-cell priming, increases mucosal sIgA, and modulates complement and cytokine tone

Top 5 Clinically Supported Benefits

1) Fewer or Shorter Upper-Respiratory Episodes (daily recovery/defense)
Randomized, placebo-controlled trials in healthy adults during winter report lower incidence and/or shorter duration of common-cold–type episodes with daily larch arabinogalactan versus placebo.
Study chips: 1.5–4.5 g/day, 8–12 weeks (seasonal) • Endpoints URTI incidence, symptom days, global severityDB-RCTs; pooled updates.

2) Mucosal Immunity (sIgA) & Immune Readiness
Controlled human studies show higher salivary secretory IgA (sIgA) with arabinogalactan supplementation—consistent with stronger first-line mucosal defense during high-exposure periods.
Study chips: 1.5–4.5 g/day, 4–8 weeks • Endpoints sIgA, illness logsRandomized/controlled.

3) Vaccine Response (adjunct signal)
In healthy adults, arabinogalactan used around vaccination has shown enhanced antibody responses to selected antigens in controlled trials—supporting a role in immune readiness (population- and antigen-dependent).
Study chips: 1.5–4.5 g/day, 4–8 weeks around vaccination • Endpoints IgG titers, seroconversionRandomized/controlled.

4) Immune Balance & Inflammation Reduction
Human trials report directionally favorable changes in CRP and pro-inflammatory cytokines (e.g., IL-6/TNF-α) with arabinogalactan, aligning with SCFA-mediated signaling and Nrf2 antioxidant pathways.
Study chips: 1.5–4.5 g/day, 6–12 weeks • Endpoints CRP, IL-6/TNF-α, TACRandomized/controlled; small–moderate cohorts.

5) Antioxidant & Gut-Barrier Support (daily resilience)
Prebiotic fermentation increases butyrate/propionate, which correlate with higher total antioxidant capacity and tight-junction support—helping maintain everyday resilience and comfort (gas/bloating typically mild/transient).
Study chips: 1.5–4.5 g/day, 4–8 weeks • Endpoints SCFAs, TAC, GI comfortRandomized/controlled.

Summary — how Arabinogalactan supports your benefits

  • Immune defense & daily recovery: Seasonal RCTs show fewer/shorter colds; higher mucosal sIgA supports first-line defense.
  • Immune balance & inflammation reduction: Fermentation-derived SCFAs help down-shift excessive NF-κB cytokine tone while preserving appropriate responses.
  • Antioxidant daily resilience: SCFA/Nrf2 signaling raises antioxidant capacity and supports barrier integrity—useful for day-to-day wellness.

Why choose Organica’s arabinogalactan

  • Clinically aligned material: native larch arabinogalactan with identity & purity confirmation; dissolves clear, low viscosity.
  • Dosing: Stand-alone trials commonly use 1.5–4.5 g/day. In Immune Armor™, we include 150–200 mg as a synergy prebiotic/immune-priming cofactor alongside elderberry, andrographis, pelargonium, tulsi, nigella, quercetin, and bromelain.
    If customers want a seasonal boost, offer an optional add-on powder to reach gram-level intake.
  • Third-party COA: identity (sugar profile), microbiology, heavy metals, pesticides, solvents; arsenic monitored (wood-derived).
  • cGMP, vegan; clean excipients.

References

  • Nutrients (2019–2024) — Reviews of arabinogalactan as a prebiotic immunomodulator, SCFAs, and mucosal immunity.
    https://www.mdpi.com/journal/nutrients
  • Nutrition & Metabolism / European Journal of Nutrition (2018–2023) — Human studies on URTI incidence/duration and sIgA with larch arabinogalactan.
    https://nutritionandmetabolism.biomedcentral.com/https://link.springer.com/journal/394
  • Journal of the American College of Nutrition / Clinical Interventions in Aging (updates) — Controlled trials on vaccine antibody responses and wellness markers.
    https://www.tandfonline.com/toc/uacn20/currenthttps://www.dovepress.com/clinical-interventions-in-aging-journal
  • Frontiers in Immunology / Frontiers in Microbiology (2020–2024) — SCFA signaling (GPR41/43), Nrf2, and barrier integrity mechanisms relevant to arabinogalactan.
    https://www.frontiersin.org/journals/immunologyhttps://www.frontiersin.org/journals/microbiology
  • Complementary Therapies in Medicine / Phytotherapy Research — Summaries of cold-season RCTs and tolerability profiles.
    https://www.sciencedirect.com/journal/complementary-therapies-in-medicinehttps://onlinelibrary.wiley.com/journal/10991573

Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Tolerability: generally excellent; mild gas/bloating can occur initially. Medication cautions: none typical at supplement doses, but individuals with immunosuppressive therapy/transplant should consult a clinician before use.

Nigella

Nigella sativa

Traditional seed extract that supports balanced immunity.

Helps maintain respiratory function
Reduces stomach inflammation
Powerful antioxidant defense

Nigella

Nigella sativa

Origin: Nigella (Nigella sativa) — standardized seed extract used for immune defense, daily recovery/resilience, antioxidant support, and immune balance/inflammation reduction. Modern products use seed extract or oil standardized for thymoquinone (TQ) (commonly 2.5–5% TQ) at ~250–500 mg/day extract (or 500–1,000 mg/day oil) over 4–12 weeks.

Phytochemical Profile

  • Key actives: thymoquinone (TQ), nigellone, thymohydroquinone, fixed oils (linoleic/oleic), and polyphenols
  • Mechanisms: NF-κB/COX-2 down-shift (inflammation), Nrf2/HO-1 up-shift (antioxidant), mast-cell/IgE moderation, and balanced Th1/Th2 immune signaling; supportive effects on airway smooth muscle and mucus dynamics
  • Caffeine-free; vegan; quality COAs declare % TQ (HPLC/UPLC)

Top 5 Clinically Supported Benefits

1) Inflammation Reduction (CRP, IL-6, TNF-α)
Meta-analyses of randomized trials in adults with inflammatory/metabolic risk show significant reductions in hs-CRP, IL-6, and TNF-α with Nigella sativa vs placebo (effect sizes modest but consistent).
Study chips: 250–2,000 mg/day (oil or TQ-std. extract) • 8–12 wk • Endpoints CRP/IL-6/TNF-αDB-RCTs; meta-analyses.

2) Antioxidant Capacity (TAC ↑; oxidative stress ↓)
Human RCTs report higher total antioxidant capacity and lower lipid peroxidation (MDA/TBARS) after nigella, aligning with Nrf2/HO-1 activation by TQ.
Study chips: 500–1,000 mg/day4–12 wk • Endpoints TAC, SOD/GPx, MDA/TBARSRandomized/controlled.

3) Immune Balance (allergy/upper-airway comfort)
Trials in allergic rhinitis and related upper-airway irritation show improved nasal/ocular symptom scores and lower IgE/eosinophil markers, consistent with mast-cell stabilization and balanced Th1/Th2 responses.
Study chips: 250–500 mg/day extract or 500–1,000 mg/day oil • 2–8 wk • Endpoints TNSS, IgE, eosinophilsDB-RCTs/controlled.

4) Respiratory Symptom Burden & Daily Recovery (adjunct)
Controlled studies—including seasonal wellness and adjunct settings—report lighter cough/congestion and quicker return to routine, supporting daily recovery during high-exposure periods.
Study chips: 500–1,000 mg/day2–8 wk • Endpoints composite symptom scores, sick-daysRandomized/controlled.

5) Cardiometabolic Co-benefits (supportive for resilience)
Meta-analyses indicate small improvements in SBP/DBP, lipids (↓ LDL-C/TG), and glycemic markers—systemic effects that underpin everyday immune resilience and inflammation control.
Study chips: 1–2 g/day oil or ~500 mg/day extract8–12 wk • Endpoints SBP/DBP, LDL-C/TG, FBG/HbA1cDB-RCTs/meta-analyses.

Summary — how Nigella supports your benefits

  • Immune balance & inflammation reduction: TQ moderates NF-κB/COX-2 and key cytokines (CRP, IL-6, TNF-α), helping the immune system respond without overreacting.
  • Antioxidant & daily resilience: Nrf2/HO-1 activation lifts endogenous defenses (TAC, SOD/GPx), easing oxidative drag.
  • Immune defense & recovery: Upper-airway studies show symptom relief and better day-to-day function during exposure seasons; allergy data highlight mast-cell/IgE moderation.

Why choose Organica’s nigella

  • Clinically aligned standardization: 2.5–5% thymoquinone (TQ) declared on label/COA.
  • Dosing: 250–500 mg/day extract (or 500–1,000 mg/day oil) for 8–12 weeks during high-exposure periods.
  • Smart stacking: pairs with quercetin (mast-cell/modulation synergy) and bromelain (airway comfort, quercetin uptake).
  • Third-party COA: identity, TQ by HPLC/UPLC, heavy metals, microbes, pesticides, solvents.
  • cGMP, vegan capsules; clean excipients.

References

  • Nutrients (2019–2024) — Systematic/umbrella reviews on Nigella sativa for inflammation, antioxidant effects, and immune outcomes.
    https://www.mdpi.com/journal/nutrients
  • Phytotherapy Research (2018–2023) — Meta-analyses/RCTs on TQ-standardized nigella: CRP/IL-6/TNF-α, allergy/upper-airway symptom scores, and metabolic markers.
    https://onlinelibrary.wiley.com/journal/10991573
  • Antioxidants (2020–2023) — Human trials: TAC ↑, oxidative stress ↓ after nigella supplementation.
    https://www.mdpi.com/journal/antioxidants
  • Evidence-Based Complementary and Alternative Medicine (2019–2023) — Clinical trials of nigella oil/extract in allergic rhinitis and respiratory symptom burden.
    https://www.hindawi.com/journals/ecam/
  • Clinical Nutrition / Complementary Therapies in Medicine (2019–2023) — Meta-analyses on blood pressure, lipids, and glycemic indices with nigella.
    https://www.sciencedirect.com/journal/clinical-nutritionhttps://www.sciencedirect.com/journal/complementary-therapies-in-medicine

Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Medication cautions: may have additive effects with anticoagulants/antiplatelets, antihypertensives, or glucose-lowering drugs. Avoid in pregnancy; consult a clinician if nursing or on chronic medications.

Supporting Ingredients

Pelargonium

Pelargonium sidoides
Geranium promotes clear airways and quicker recovery.
Helps maintain clear airways
Promotes efficient mucus clearance
Supports faster bounce-back

Pelargonium

Pelargonium sidoides

Origin: Pelargonium (Pelargonium sidoides) — standardized root extract used for immune defense, daily recovery, and inflammation reduction, with consistent human evidence for shortening upper-respiratory symptom duration and easing cough/throat discomfort. Most clinical work uses an EPs-style root extract; adult protocols commonly span 7–10 days during acute episodes (capsules/tablets or liquid), and 2–3 weeks in high-exposure periods.

Phytochemical Profile

  • Coumarins (e.g., umckalin derivatives), proanthocyanidins, and other polyphenols
  • Mechanisms: mucociliary support, anti-adhesion effects on respiratory pathogens (helps clearance), balanced immune modulation (innate support without overstimulation), and NF-κB/COX-2 down-shift with antioxidant (Nrf2) activity
  • Caffeine-free; vegan; quality COAs confirm botanical ID and marker compounds for EPs-style extracts

Top 5 Clinically Supported Benefits

1) Faster Daily Recovery (URTI duration & severity ↓)
Randomized, placebo-controlled trials and meta-analyses show shorter duration and lower overall severity of common-cold/acute bronchitis symptoms with standardized P. sidoides vs placebo. Benefits typically appear within 2–3 days and accumulate over 7–10 days.
Study chips: ~60 mg/day EPs-style extract (or labeled equivalent) • 7–10 days • Endpoints symptom-day counts, composite severity, rescue-meds useDB-RCTs; meta-analyses.

2) Cough & Throat Comfort
Trials consistently report reduced cough frequency/severity, easier expectoration, and less throat pain, supporting daily recovery and return to normal activity.
Study chips: same as above • Endpoints cough scores, sputum ease, throat-pain VASDB-RCTs.

3) Immune Defense / Fewer Complications (adjunctive signal)
Across controlled studies, P. sidoides groups show lower odds of symptom progression and fewer “rescue” medications (e.g., antitussives/antibiotics)—consistent with improved immune efficiency and airway clearance.
Study chips: 7–10 days • Endpoints treatment failures, adjunct medication rates, physician-rated improvementDB-RCTs; pooled analyses.

4) Inflammation Reduction & Antioxidant Support
Human and translational data indicate decreases in inflammatory indices (e.g., CRP trends in at-risk cohorts) and improved antioxidant capacity, aligning with NF-κB down-modulation and phenolic antioxidant activity.
Study chips: 1–3 weeks • Endpoints CRP/IL-6 (study-specific), TAC/MDARandomized/controlled; small–moderate cohorts.

5) Daily Resilience (function & well-being)
Patient-reported outcomes show quicker return to normal routine, less sleep disruption from cough, and improved global well-being during seasonal use.
Study chips: 1–3 weeks • Endpoints global wellness, activity scales, sleep impactRCTs/controlled studies.

Summary — how Pelargonium supports your benefits

  • Immune defense & daily recovery: Speeds resolution of cold-like symptoms (especially cough/throat), helping you bounce back sooner.
  • Immune balance & inflammation reduction: Modulates airway inflammation (NF-κB/COX-2) and supports mucociliary clearance without “over-amping” immunity.
  • Antioxidant daily resilience: Polyphenols bolster redox defenses during high-exposure periods.

Why choose Organica’s pelargonium

  • Clinically aligned extract: EPs-style root extract with verified marker profile (coumarins/proanthocyanidins).
  • Clear protocols: Acute: ~60 mg/day for 7–10 days at first signs. Seasonal: 2–3 weeks during high-exposure windows.
  • Third-party COA: identity (macroscopy/microscopy/DNA as appropriate), marker panel (HPLC/UPLC), heavy metals, microbes, pesticides, solvents.
  • cGMP, vegan capsules; clean excipients.

References

  • Phytomedicine / Phytotherapy Research (2018–2023) — Systematic reviews & meta-analyses of Pelargonium sidoides in acute respiratory infections (duration, severity, cough).
    https://www.journals.elsevier.com/phytomedicinehttps://onlinelibrary.wiley.com/journal/10991573
  • Complementary Therapies in Medicine (2018–2022) — Randomized trials of EPs-style extracts for common cold/acute bronchitis (adult & pediatric subsets).
    https://www.sciencedirect.com/journal/complementary-therapies-in-medicine
  • Nutrients (2020–2023) — Reviews on botanical immune modulators; P. sidoides mechanisms (anti-adhesion, mucociliary, cytokine balance).
    https://www.mdpi.com/journal/nutrients
  • Frontiers in Pharmacology (2020–2024) — Mechanistic overviews of P. sidoides constituents, airway inflammation, and antiviral entry models.
    https://www.frontiersin.org/journals/pharmacology
  • Advances in Integrative Medicine / Evidence-Based Complementary and Alternative Medicine (2019–2023) — Clinical summaries & safety appraisals.
    https://www.journals.elsevier.com/advances-in-integrative-medicinehttps://www.hindawi.com/journals/ecam/

Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Avoid if pregnant/nursing. Use caution with anticoagulants/antiplatelets or bleeding disorders. Rare GI upset or allergic reactions can occur; discontinue if adverse symptoms appear.

Astragalus

Astragalus membranaceus
Sustains everyday immune stamina and NK-cell readiness.
Helps maintain healthy cell activity
Supports everyday immune readiness
Complements balance and resilience

Astragalus

Astragalus membranaceus

Origin: Astragalus (Astragalus membranaceus) — standardized root extract used for immune defense, daily resilience/recovery, and immune balance. Modern products declare polysaccharides (e.g., ≥16–40%) and sometimes astragaloside IV (e.g., ≥0.5%) on the COA; protocols span seasonal daily use (4–12 weeks) and acute support at first signs.

Phytochemical Profile

  • Astragalus polysaccharides (APS), astragalosides (incl. astragaloside IV), flavonoids (calycosin, formononetin)
  • Mechanisms: balanced immune modulation (innate/NK activity, antibody responses), cytokine homeostasis (downshifts excessive NF-κB/IL-6/TNF-α), and antioxidant/Nrf2 support
  • Caffeine-free; vegan; quality extracts list % polysaccharides (and astragaloside IV where applicable)

Top 5 Clinically Supported Benefits

1) Immune Defense: fewer URTI episodes/shorter duration
Randomized and controlled human studies using standardized astragalus report lower incidence of common colds over seasonal windows and/or shorter symptom duration versus placebo or routine care.
Study chips: 200–600 mg/day extract (or 1–3 g/day root equivalent) • 4–12 wk • Endpoints URTI incidence, symptom days/severity • Design DB-RCTs/controlled trials.

2) Daily Resilience & Recovery
Trials in at-risk adults (e.g., high-stress/older) show improvements in well-being/fatigue indices and faster return to normal function during cold season when astragalus is taken preventively.
Study chips: 200–500 mg/day6–12 wk • Endpoints fatigue scales, global well-being, sick-days • Design randomized/controlled.

3) Immune Balance (cytokines) & Inflammation Reduction
Human studies report directionally favorable changes in CRP, IL-6, and TNF-α, consistent with NF-κB modulation and a balanced (not overstimulated) immune profile.
Study chips: 200–600 mg/day4–12 wk • Endpoints CRP, IL-6, TNF-α • Design randomized/controlled; small–moderate cohorts.

4) Antioxidant Capacity (TAC, SOD/GPx)
Supplementation has been associated with higher total antioxidant capacity and upregulated SOD/GPx with lower lipid peroxidation (MDA/TBARS)—supporting daily resilience.
Study chips: 200–500 mg/day4–8 wk • Endpoints TAC, SOD/GPx, MDA/TBARS • Design randomized/controlled.

5) Vaccine/Antibody Response (adjunct signals)
Pilot human studies indicate enhanced antibody titers or immune-readiness markers when astragalus is used as a seasonal adjunct (population- and vaccine-dependent; confirmation ongoing).
Study chips: 200–500 mg/day4–8 wk • Endpoints specific antibody titers, NK activity • Design controlled trials; exploratory

Summary — how Astragalus supports your benefits

  • Immune defense & daily resilience: APS and astragalosides help reduce URTI incidence and shorten duration, while improving well-being/fatigue in seasonal use.
  • Immune balance & inflammation reduction: Calms excess inflammatory signaling (NF-κB/IL-6/TNF-α) without bluntly “amping” immunity.
  • Antioxidant: Boosts endogenous defenses (SOD/GPx), buffering everyday oxidative stress.

Why choose Organica’s astragalus

  • Clinically aligned standardization: ≥16% polysaccharides and ≥0.5% astragaloside IV (declared on label/COA).
  • Clear protocols: Preventive: 200–600 mg/day for 4–12 weeks. At first signs: maintain daily dose with the rest of the stack.
  • Third-party COA: identity (botanical/DNA), polysaccharides & astragaloside IV (HPLC/UPLC), heavy metals, microbes, pesticides, solvents.
  • cGMP, vegan capsules; clean excipients.

References

  • Nutrients (2019–2023) — Human-focused reviews of Astragalus membranaceus for immune modulation, antioxidant effects, and seasonal wellness.
    https://www.mdpi.com/journal/nutrients
  • Phytotherapy Research (2018–2023) — RCTs/meta-analyses of astragalus for URTI prevention and immune markers (APS/astragaloside IV).
    https://onlinelibrary.wiley.com/journal/10991573
  • Frontiers in Pharmacology (2020–2024) — Mechanistic overviews: APS on NF-κB, cytokines, and antibody/NK activity.
    https://www.frontiersin.org/journals/pharmacology
  • Evidence-Based Complementary and Alternative Medicine (2019–2022) — Controlled trials on fatigue/well-being and oxidative markers with astragalus.
    https://www.hindawi.com/journals/ecam/
  • Journal of Ethnopharmacology / Integrative Medicine Research (2018–2023) — Clinical summaries on astragalus for seasonal respiratory support.
    https://www.sciencedirect.com/journal/journal-of-ethnopharmacologyhttps://www.elsevier.com/journals/integrative-medicine-research

Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Avoid use with immunosuppressive therapy/transplant unless supervised. Consult a clinician if pregnant/nursing or on anticoagulants.

Andrographis

Andrographis paniculata
Rapid immune support and balanced inflammation.
Helps ease seasonal symptoms
Balances inflammatory response
Promotes quicker recovery

Andrographis

Andrographis paniculata

Andrographis (Andrographis paniculata) — standardized aerial-part extract used for immune defense, daily recovery, and inflammation reduction, with consistent human data for shortening upper-respiratory symptom duration and easing severity. Modern products declare andrographolides (e.g., ≥20%) on the COA; protocols span acute 5–10 days and seasonal 4–12 weeks.

Phytochemical Profile

  • Diterpene lactones: andrographolide, neoandrographolide, deoxy-/14-deoxy-andrographolides
  • Mechanisms: balanced immune modulation (innate/Th1 support without overstimulation), NF-κB/STAT down-shift, antioxidant/Nrf2 support; upper-airway symptom relief seen in trials
  • Caffeine-free; vegan; quality extracts list % andrographolides (HPLC/UPLC)

Top 5 Clinically Supported Benefits

1) Faster Daily Recovery (URTI duration ↓, severity ↓)
Meta-analyses and randomized, placebo-controlled trials report shorter duration and lower severity of common-cold/URTI symptoms (sore throat, cough, nasal symptoms, fever) with standardized andrographis versus placebo.
Study chips: 200–400 mg/day extract (≥20% andrographolides) • 5–10 days acute use • Endpoints symptom days, composite severity, rescue-medsDB-RCTs; meta-analyses.

2) Immune Defense / Fewer Episodes (seasonal use)
Controlled human studies show reduced incidence or fewer sick-days across high-exposure seasons when andrographis is taken preventively.
Study chips: 200–600 mg/day4–12 weeks • Endpoints URTI incidence, sick-days, absenteeismRandomized/controlled.

3) Inflammation Reduction & Throat Comfort
Trials document greater reductions in throat pain scores, cough intensity/frequency, and fever days, aligning with NF-κB/COX-2 modulation and local anti-inflammatory actions.
Study chips: 200–400 mg/day5–10 days • Endpoints pain VAS, cough scores, fever daysDB-RCTs.

4) Antioxidant / Daily Resilience (marker support)
Human studies (ill and at-risk adults) report improvements in oxidative-stress markers and directionally favorable shifts in CRP/IL-6, consistent with andrographolide-driven redox and cytokine balance.
Study chips: 200–600 mg/day2–8 weeks • Endpoints TAC, MDA/TBARS, CRP/IL-6Randomized/controlled; small-to-moderate cohorts.

5) Tolerability & Safety Signals
Standardized extracts are generally well tolerated in RCTs, with AE rates similar to placebo (most often mild GI upset or transient headache).
Study chips: Up to 12 weeks • Endpoints AEs, discontinuationsDB-RCTs/meta-analyses.

Summary — how Andrographis supports your benefits

  • Immune defense & daily recovery: Consistently shortens URTI duration and lightens symptom load (throat/cough/fever).
  • Immune balance & inflammation reduction: Damps NF-κB/STAT–mediated signaling while supporting appropriate innate responses—useful for everyday wellness without overstimulation.
  • Antioxidant daily resilience: Supports redox balance during high-exposure periods.

Why choose Organica’s andrographis

  • Clinically aligned standardization:20% andrographolides, batch-verified; single-herb (not blended) so dose is clear.
  • Clear protocols: Acute: 200–400 mg/day for 5–10 days at first signs. Seasonal: 200–600 mg/day for 4–12 weeks.
  • Third-party COA: identity, andrographolides (HPLC/UPLC), heavy metals, microbes, pesticides, solvents.
  • cGMP, vegan capsules; clean excipients.

References

  • Phytotherapy Research (2019–2023). Systematic reviews/meta-analyses of A. paniculata for URTI (duration, severity, throat/cough outcomes).
    https://onlinelibrary.wiley.com/journal/10991573
  • Nutrients (2020–2023). Reviews on immune-modulating botanicals; andrographis mechanisms (NF-κB/STAT) and clinical updates.
    https://www.mdpi.com/journal/nutrients
  • Complementary Therapies in Medicine (2018–2022). Randomized trials of standardized andrographis for common cold/URTI; pooled analyses.
    https://www.sciencedirect.com/journal/complementary-therapies-in-medicine
  • Journal of Herbal Medicine / Phytomedicine (2019–2022). Clinical evidence summaries and dosing guidance for andrographolide-standardized extracts.
    https://www.sciencedirect.com/journal/journal-of-herbal-medicinehttps://www.journals.elsevier.com/phytomedicine
  • Frontiers in Pharmacology (2020–2024). Mechanistic overviews of andrographolide (cytokine signaling, redox, antiviral entry models).
    https://www.frontiersin.org/journals/pharmacology

Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Not for pregnancy or breastfeeding. Use caution with anticoagulants/antiplatelets (additive effects possible). Stop 1–2 weeks before surgery unless advised. Rare hypersensitivity or taste changes can occur; discontinue if rash or persistent GI upset develops.

Clinical Research for Arabinogalactan

Arabinogalactan

Larch Arabinogalactan

Prebiotic larch fiber that strengthens mucosal immunity.

Promotes fewer seasonal cold episodes
Boosts mucosal sIgA levels
Prebiotic SCFAs antioxidant resilience
George Wagner
PHD in Nutritional Sciences

Arabinogalactan

Larch Arabinogalactan

Arabinogalactan (from Larch, Larix spp.) — standardized prebiotic polysaccharide used for immune defense, daily recovery/resilience, immune balance, inflammation reduction, and antioxidant support. Modern products use highly soluble, low-viscosity fibers composed of β-1,3 galactan backbones with arabinosyl side chains; they dissolve clear, are mildly sweet, and are well tolerated.

Phytochemical Profile

  • Branched arabinose–galactose polysaccharides (typically >85% fiber) from larch wood
  • Prebiotic fermentation → SCFAs (butyrate/propionate) that signal via GPR41/43, supporting barrier integrity, immune balance, and oxidative-stress control (Nrf2)
  • Immunology: supports dendritic/NK-cell priming, increases mucosal sIgA, and modulates complement and cytokine tone

Top 5 Clinically Supported Benefits

1) Fewer or Shorter Upper-Respiratory Episodes (daily recovery/defense)
Randomized, placebo-controlled trials in healthy adults during winter report lower incidence and/or shorter duration of common-cold–type episodes with daily larch arabinogalactan versus placebo.
Study chips: 1.5–4.5 g/day, 8–12 weeks (seasonal) • Endpoints URTI incidence, symptom days, global severityDB-RCTs; pooled updates.

2) Mucosal Immunity (sIgA) & Immune Readiness
Controlled human studies show higher salivary secretory IgA (sIgA) with arabinogalactan supplementation—consistent with stronger first-line mucosal defense during high-exposure periods.
Study chips: 1.5–4.5 g/day, 4–8 weeks • Endpoints sIgA, illness logsRandomized/controlled.

3) Vaccine Response (adjunct signal)
In healthy adults, arabinogalactan used around vaccination has shown enhanced antibody responses to selected antigens in controlled trials—supporting a role in immune readiness (population- and antigen-dependent).
Study chips: 1.5–4.5 g/day, 4–8 weeks around vaccination • Endpoints IgG titers, seroconversionRandomized/controlled.

4) Immune Balance & Inflammation Reduction
Human trials report directionally favorable changes in CRP and pro-inflammatory cytokines (e.g., IL-6/TNF-α) with arabinogalactan, aligning with SCFA-mediated signaling and Nrf2 antioxidant pathways.
Study chips: 1.5–4.5 g/day, 6–12 weeks • Endpoints CRP, IL-6/TNF-α, TACRandomized/controlled; small–moderate cohorts.

5) Antioxidant & Gut-Barrier Support (daily resilience)
Prebiotic fermentation increases butyrate/propionate, which correlate with higher total antioxidant capacity and tight-junction support—helping maintain everyday resilience and comfort (gas/bloating typically mild/transient).
Study chips: 1.5–4.5 g/day, 4–8 weeks • Endpoints SCFAs, TAC, GI comfortRandomized/controlled.

Summary — how Arabinogalactan supports your benefits

  • Immune defense & daily recovery: Seasonal RCTs show fewer/shorter colds; higher mucosal sIgA supports first-line defense.
  • Immune balance & inflammation reduction: Fermentation-derived SCFAs help down-shift excessive NF-κB cytokine tone while preserving appropriate responses.
  • Antioxidant daily resilience: SCFA/Nrf2 signaling raises antioxidant capacity and supports barrier integrity—useful for day-to-day wellness.

Why choose Organica’s arabinogalactan

  • Clinically aligned material: native larch arabinogalactan with identity & purity confirmation; dissolves clear, low viscosity.
  • Dosing: Stand-alone trials commonly use 1.5–4.5 g/day. In Immune Armor™, we include 150–200 mg as a synergy prebiotic/immune-priming cofactor alongside elderberry, andrographis, pelargonium, tulsi, nigella, quercetin, and bromelain.
    If customers want a seasonal boost, offer an optional add-on powder to reach gram-level intake.
  • Third-party COA: identity (sugar profile), microbiology, heavy metals, pesticides, solvents; arsenic monitored (wood-derived).
  • cGMP, vegan; clean excipients.

References

  • Nutrients (2019–2024) — Reviews of arabinogalactan as a prebiotic immunomodulator, SCFAs, and mucosal immunity.
    https://www.mdpi.com/journal/nutrients
  • Nutrition & Metabolism / European Journal of Nutrition (2018–2023) — Human studies on URTI incidence/duration and sIgA with larch arabinogalactan.
    https://nutritionandmetabolism.biomedcentral.com/https://link.springer.com/journal/394
  • Journal of the American College of Nutrition / Clinical Interventions in Aging (updates) — Controlled trials on vaccine antibody responses and wellness markers.
    https://www.tandfonline.com/toc/uacn20/currenthttps://www.dovepress.com/clinical-interventions-in-aging-journal
  • Frontiers in Immunology / Frontiers in Microbiology (2020–2024) — SCFA signaling (GPR41/43), Nrf2, and barrier integrity mechanisms relevant to arabinogalactan.
    https://www.frontiersin.org/journals/immunologyhttps://www.frontiersin.org/journals/microbiology
  • Complementary Therapies in Medicine / Phytotherapy Research — Summaries of cold-season RCTs and tolerability profiles.
    https://www.sciencedirect.com/journal/complementary-therapies-in-medicinehttps://onlinelibrary.wiley.com/journal/10991573

Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Tolerability: generally excellent; mild gas/bloating can occur initially. Medication cautions: none typical at supplement doses, but individuals with immunosuppressive therapy/transplant should consult a clinician before use.

Pelargonium

Pelargonium sidoides

Geranium promotes clear airways and quicker recovery.

Helps maintain clear airways
Promotes efficient mucus clearance
Supports faster bounce-back
George Wagner
PHD in Nutritional Sciences

Pelargonium

Pelargonium sidoides

Origin: Pelargonium (Pelargonium sidoides) — standardized root extract used for immune defense, daily recovery, and inflammation reduction, with consistent human evidence for shortening upper-respiratory symptom duration and easing cough/throat discomfort. Most clinical work uses an EPs-style root extract; adult protocols commonly span 7–10 days during acute episodes (capsules/tablets or liquid), and 2–3 weeks in high-exposure periods.

Phytochemical Profile

  • Coumarins (e.g., umckalin derivatives), proanthocyanidins, and other polyphenols
  • Mechanisms: mucociliary support, anti-adhesion effects on respiratory pathogens (helps clearance), balanced immune modulation (innate support without overstimulation), and NF-κB/COX-2 down-shift with antioxidant (Nrf2) activity
  • Caffeine-free; vegan; quality COAs confirm botanical ID and marker compounds for EPs-style extracts

Top 5 Clinically Supported Benefits

1) Faster Daily Recovery (URTI duration & severity ↓)
Randomized, placebo-controlled trials and meta-analyses show shorter duration and lower overall severity of common-cold/acute bronchitis symptoms with standardized P. sidoides vs placebo. Benefits typically appear within 2–3 days and accumulate over 7–10 days.
Study chips: ~60 mg/day EPs-style extract (or labeled equivalent) • 7–10 days • Endpoints symptom-day counts, composite severity, rescue-meds useDB-RCTs; meta-analyses.

2) Cough & Throat Comfort
Trials consistently report reduced cough frequency/severity, easier expectoration, and less throat pain, supporting daily recovery and return to normal activity.
Study chips: same as above • Endpoints cough scores, sputum ease, throat-pain VASDB-RCTs.

3) Immune Defense / Fewer Complications (adjunctive signal)
Across controlled studies, P. sidoides groups show lower odds of symptom progression and fewer “rescue” medications (e.g., antitussives/antibiotics)—consistent with improved immune efficiency and airway clearance.
Study chips: 7–10 days • Endpoints treatment failures, adjunct medication rates, physician-rated improvementDB-RCTs; pooled analyses.

4) Inflammation Reduction & Antioxidant Support
Human and translational data indicate decreases in inflammatory indices (e.g., CRP trends in at-risk cohorts) and improved antioxidant capacity, aligning with NF-κB down-modulation and phenolic antioxidant activity.
Study chips: 1–3 weeks • Endpoints CRP/IL-6 (study-specific), TAC/MDARandomized/controlled; small–moderate cohorts.

5) Daily Resilience (function & well-being)
Patient-reported outcomes show quicker return to normal routine, less sleep disruption from cough, and improved global well-being during seasonal use.
Study chips: 1–3 weeks • Endpoints global wellness, activity scales, sleep impactRCTs/controlled studies.

Summary — how Pelargonium supports your benefits

  • Immune defense & daily recovery: Speeds resolution of cold-like symptoms (especially cough/throat), helping you bounce back sooner.
  • Immune balance & inflammation reduction: Modulates airway inflammation (NF-κB/COX-2) and supports mucociliary clearance without “over-amping” immunity.
  • Antioxidant daily resilience: Polyphenols bolster redox defenses during high-exposure periods.

Why choose Organica’s pelargonium

  • Clinically aligned extract: EPs-style root extract with verified marker profile (coumarins/proanthocyanidins).
  • Clear protocols: Acute: ~60 mg/day for 7–10 days at first signs. Seasonal: 2–3 weeks during high-exposure windows.
  • Third-party COA: identity (macroscopy/microscopy/DNA as appropriate), marker panel (HPLC/UPLC), heavy metals, microbes, pesticides, solvents.
  • cGMP, vegan capsules; clean excipients.

References

  • Phytomedicine / Phytotherapy Research (2018–2023) — Systematic reviews & meta-analyses of Pelargonium sidoides in acute respiratory infections (duration, severity, cough).
    https://www.journals.elsevier.com/phytomedicinehttps://onlinelibrary.wiley.com/journal/10991573
  • Complementary Therapies in Medicine (2018–2022) — Randomized trials of EPs-style extracts for common cold/acute bronchitis (adult & pediatric subsets).
    https://www.sciencedirect.com/journal/complementary-therapies-in-medicine
  • Nutrients (2020–2023) — Reviews on botanical immune modulators; P. sidoides mechanisms (anti-adhesion, mucociliary, cytokine balance).
    https://www.mdpi.com/journal/nutrients
  • Frontiers in Pharmacology (2020–2024) — Mechanistic overviews of P. sidoides constituents, airway inflammation, and antiviral entry models.
    https://www.frontiersin.org/journals/pharmacology
  • Advances in Integrative Medicine / Evidence-Based Complementary and Alternative Medicine (2019–2023) — Clinical summaries & safety appraisals.
    https://www.journals.elsevier.com/advances-in-integrative-medicinehttps://www.hindawi.com/journals/ecam/

Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Avoid if pregnant/nursing. Use caution with anticoagulants/antiplatelets or bleeding disorders. Rare GI upset or allergic reactions can occur; discontinue if adverse symptoms appear.

Quercetin

Sophora japonica

Stabilizes mast cells production and supports sinus comfort.

Supports mast-cell immune stability
Broad antioxidant superfood
Significantly reduces inflammation
George Wagner
PHD in Nutritional Sciences

Quercetin

Sophora japonica

Origin: Quercetin — standardized flavonol (typically from Sophora japonica) used for immune defense, daily resilience/recovery, antioxidant support, and immune balance/inflammation reduction. Modern supplements use quercetin anhydrous/dihydrate, or enhanced-bioavailability forms (e.g., Quercetin Phytosome/Quercefit®, EMIQ/isoquercitrin) at ~250–500 mg/day (anhydrous equivalents), often paired with bromelain or vitamin C.

Phytochemical Profile

  • Core actions: NF-κB/COX-2 down-shift (inflammation), Nrf2/HO-1 up-shift (antioxidant), mast-cell stabilization (histamine moderation), endothelial/immune signaling balance
  • Forms & absorption: phytosome and glycosylated forms (EMIQ) yield higher plasma levels vs plain quercetin; bromelain may aid uptake
  • Vegan, non-GMO; quality COAs declare ≥95% quercetin (or equivalence for phytosome/EMIQ)

Top 5 Clinically Supported Benefits

1) Inflammation Reduction (CRP, IL-6, TNF-α)
Meta-analyses of randomized trials in adults with metabolic/inflammatory risk show reductions in hs-CRP, IL-6, and TNF-α with quercetin versus placebo—effect sizes modest but significant.
Study chips: 250–1,000 mg/day (or bioavailable equivalents) • 8–12 wk • Endpoints CRP/hs-CRP, IL-6, TNF-α • Design DB-RCTs; pooled analyses.
Benefit tags: immune balance · inflammation reduction

2) Antioxidant Capacity (TAC ↑; oxidative stress ↓)
Human RCTs report higher total antioxidant capacity (TAC) and lower lipid peroxidation (e.g., MDA/TBARS) with quercetin supplementation—consistent with Nrf2/HO-1 activation.
Study chips: 250–500 mg/day4–12 wk • Endpoints TAC, SOD/GPx, MDA/TBARSRandomized/controlled.
Benefit tags: antioxidant · daily resilience

3) Upper-Respiratory Symptom Load (adjunct human signals)
Recent controlled trials (including combination formulas with vitamin C ± bromelain) show reduced URTI symptom days/severity or fewer sick days, while some trials of quercetin alone are neutral—overall signal favors adjunctive use for daily recovery.
Study chips: 500–1,000 mg/day quercetin (or bioavailable equivalent), sometimes with vitamin C/bromelain • 2–12 wk • Endpoints symptom days, composite scores, sick-daysDB-RCTs.
Benefit tags: immune defense · daily recovery

4) Allergy/Upper-Airway Comfort (mast-cell stabilization)
Pilot RCTs and controlled studies report improved nasal/ocular symptom scores in seasonal-allergy contexts with bioavailable quercetin—consistent with histamine moderation and local anti-inflammatory effects.
Study chips: ~250–500 mg/day (bioavailable forms favored) • 2–8 wk • Endpoints TNSS/eye symptom scales, rescue-meds useRandomized/controlled.
Benefit tags: immune balance · daily resilience

5) Cardiometabolic Support (secondary but supportive)
Meta-analyses since 2018 indicate small reductions in SBP/DBP and improved glycemic markers in at-risk adults—reflecting systemic anti-inflammatory/antioxidant effects that underpin everyday immune resilience.
Study chips: 500–1,000 mg/day8–12 wk • Endpoints SBP/DBP, FBG/HbA1cDB-RCTs/meta-analyses.
Benefit tags: inflammation reduction · antioxidant

Summary — how Quercetin supports your benefits

  • Immune balance & inflammation reduction: Down-regulates NF-κB/COX-2 and moderates cytokines (CRP/IL-6/TNF-α), helping the immune system respond without overreacting.
  • Antioxidant daily resilience: Activates Nrf2/HO-1, raising endogenous defenses (TAC, SOD/GPx) and lowering oxidative burden.
  • Immune defense & daily recovery: As a stand-alone or adjunct with vitamin C/bromelain, quercetin shows human signals for lighter, shorter respiratory symptom loads—useful during high-exposure seasons.

Why choose Organica’s quercetin

  • Clinically aligned dosing: 250–500 mg/day (anhydrous equivalent) in 1–2 caps.
  • Enhanced uptake option: Phytosome (Quercetin Phytosome/Quercefit®) or EMIQ for higher plasma exposure at lower mg.
  • Smart pairing: We include bromelain in Immune Armor™ to aid absorption and add upper-airway comfort.
  • Third-party COA: identity, assay (HPLC/UPLC), heavy metals, microbes, pesticides, solvents.
  • cGMP, vegan capsules; clean excipients.

References

  • Phytotherapy Research (2019–2023) — Meta-analyses/RCTs on quercetin and CRP/IL-6/TNF-α; inflammation outcomes.
    https://onlinelibrary.wiley.com/journal/10991573
  • Nutrients (2020–2024) — Reviews on quercetin bioavailability (phytosome/EMIQ), immune modulation, and respiratory wellness.
    https://www.mdpi.com/journal/nutrients
  • Antioxidants (2020–2023) — Human trials: TAC ↑, oxidative stress ↓ with quercetin supplementation.
    https://www.mdpi.com/journal/antioxidants
  • Clinical Nutrition / Nutrition Reviews (2019–2023) — Meta-analyses on blood pressure and glycemic markers with quercetin.
    https://www.sciencedirect.com/journal/clinical-nutritionhttps://academic.oup.com/nutritionreviews
  • Complementary Therapies in Medicine / Evidence-Based CAM (2019–2023) — RCTs of quercetin (± vitamin C/bromelain) on URTI symptom days/severity.
    https://www.sciencedirect.com/journal/complementary-therapies-in-medicinehttps://www.hindawi.com/journals/ecam/

Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Medication cautions: quercetin may affect drug metabolism (e.g., CYP3A4/P-gp); consult a clinician if using anticoagulants, chemotherapy, antibiotics, or other critical meds. Not recommended in pregnancy/nursing without medical guidance.

Nigella

Nigella sativa

Traditional seed extract that supports balanced immunity.

Helps maintain respiratory function
Reduces stomach inflammation
Powerful antioxidant defense
George Wagner
PHD in Nutritional Sciences

Nigella

Nigella sativa

Origin: Nigella (Nigella sativa) — standardized seed extract used for immune defense, daily recovery/resilience, antioxidant support, and immune balance/inflammation reduction. Modern products use seed extract or oil standardized for thymoquinone (TQ) (commonly 2.5–5% TQ) at ~250–500 mg/day extract (or 500–1,000 mg/day oil) over 4–12 weeks.

Phytochemical Profile

  • Key actives: thymoquinone (TQ), nigellone, thymohydroquinone, fixed oils (linoleic/oleic), and polyphenols
  • Mechanisms: NF-κB/COX-2 down-shift (inflammation), Nrf2/HO-1 up-shift (antioxidant), mast-cell/IgE moderation, and balanced Th1/Th2 immune signaling; supportive effects on airway smooth muscle and mucus dynamics
  • Caffeine-free; vegan; quality COAs declare % TQ (HPLC/UPLC)

Top 5 Clinically Supported Benefits

1) Inflammation Reduction (CRP, IL-6, TNF-α)
Meta-analyses of randomized trials in adults with inflammatory/metabolic risk show significant reductions in hs-CRP, IL-6, and TNF-α with Nigella sativa vs placebo (effect sizes modest but consistent).
Study chips: 250–2,000 mg/day (oil or TQ-std. extract) • 8–12 wk • Endpoints CRP/IL-6/TNF-αDB-RCTs; meta-analyses.

2) Antioxidant Capacity (TAC ↑; oxidative stress ↓)
Human RCTs report higher total antioxidant capacity and lower lipid peroxidation (MDA/TBARS) after nigella, aligning with Nrf2/HO-1 activation by TQ.
Study chips: 500–1,000 mg/day4–12 wk • Endpoints TAC, SOD/GPx, MDA/TBARSRandomized/controlled.

3) Immune Balance (allergy/upper-airway comfort)
Trials in allergic rhinitis and related upper-airway irritation show improved nasal/ocular symptom scores and lower IgE/eosinophil markers, consistent with mast-cell stabilization and balanced Th1/Th2 responses.
Study chips: 250–500 mg/day extract or 500–1,000 mg/day oil • 2–8 wk • Endpoints TNSS, IgE, eosinophilsDB-RCTs/controlled.

4) Respiratory Symptom Burden & Daily Recovery (adjunct)
Controlled studies—including seasonal wellness and adjunct settings—report lighter cough/congestion and quicker return to routine, supporting daily recovery during high-exposure periods.
Study chips: 500–1,000 mg/day2–8 wk • Endpoints composite symptom scores, sick-daysRandomized/controlled.

5) Cardiometabolic Co-benefits (supportive for resilience)
Meta-analyses indicate small improvements in SBP/DBP, lipids (↓ LDL-C/TG), and glycemic markers—systemic effects that underpin everyday immune resilience and inflammation control.
Study chips: 1–2 g/day oil or ~500 mg/day extract8–12 wk • Endpoints SBP/DBP, LDL-C/TG, FBG/HbA1cDB-RCTs/meta-analyses.

Summary — how Nigella supports your benefits

  • Immune balance & inflammation reduction: TQ moderates NF-κB/COX-2 and key cytokines (CRP, IL-6, TNF-α), helping the immune system respond without overreacting.
  • Antioxidant & daily resilience: Nrf2/HO-1 activation lifts endogenous defenses (TAC, SOD/GPx), easing oxidative drag.
  • Immune defense & recovery: Upper-airway studies show symptom relief and better day-to-day function during exposure seasons; allergy data highlight mast-cell/IgE moderation.

Why choose Organica’s nigella

  • Clinically aligned standardization: 2.5–5% thymoquinone (TQ) declared on label/COA.
  • Dosing: 250–500 mg/day extract (or 500–1,000 mg/day oil) for 8–12 weeks during high-exposure periods.
  • Smart stacking: pairs with quercetin (mast-cell/modulation synergy) and bromelain (airway comfort, quercetin uptake).
  • Third-party COA: identity, TQ by HPLC/UPLC, heavy metals, microbes, pesticides, solvents.
  • cGMP, vegan capsules; clean excipients.

References

  • Nutrients (2019–2024) — Systematic/umbrella reviews on Nigella sativa for inflammation, antioxidant effects, and immune outcomes.
    https://www.mdpi.com/journal/nutrients
  • Phytotherapy Research (2018–2023) — Meta-analyses/RCTs on TQ-standardized nigella: CRP/IL-6/TNF-α, allergy/upper-airway symptom scores, and metabolic markers.
    https://onlinelibrary.wiley.com/journal/10991573
  • Antioxidants (2020–2023) — Human trials: TAC ↑, oxidative stress ↓ after nigella supplementation.
    https://www.mdpi.com/journal/antioxidants
  • Evidence-Based Complementary and Alternative Medicine (2019–2023) — Clinical trials of nigella oil/extract in allergic rhinitis and respiratory symptom burden.
    https://www.hindawi.com/journals/ecam/
  • Clinical Nutrition / Complementary Therapies in Medicine (2019–2023) — Meta-analyses on blood pressure, lipids, and glycemic indices with nigella.
    https://www.sciencedirect.com/journal/clinical-nutritionhttps://www.sciencedirect.com/journal/complementary-therapies-in-medicine

Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Medication cautions: may have additive effects with anticoagulants/antiplatelets, antihypertensives, or glucose-lowering drugs. Avoid in pregnancy; consult a clinician if nursing or on chronic medications.

Astragalus

Astragalus membranaceus

Sustains everyday immune stamina and NK-cell readiness.

Helps maintain healthy cell activity
Supports everyday immune readiness
Complements balance and resilience
George Wagner
PHD in Nutritional Sciences

Astragalus

Astragalus membranaceus

Origin: Astragalus (Astragalus membranaceus) — standardized root extract used for immune defense, daily resilience/recovery, and immune balance. Modern products declare polysaccharides (e.g., ≥16–40%) and sometimes astragaloside IV (e.g., ≥0.5%) on the COA; protocols span seasonal daily use (4–12 weeks) and acute support at first signs.

Phytochemical Profile

  • Astragalus polysaccharides (APS), astragalosides (incl. astragaloside IV), flavonoids (calycosin, formononetin)
  • Mechanisms: balanced immune modulation (innate/NK activity, antibody responses), cytokine homeostasis (downshifts excessive NF-κB/IL-6/TNF-α), and antioxidant/Nrf2 support
  • Caffeine-free; vegan; quality extracts list % polysaccharides (and astragaloside IV where applicable)

Top 5 Clinically Supported Benefits

1) Immune Defense: fewer URTI episodes/shorter duration
Randomized and controlled human studies using standardized astragalus report lower incidence of common colds over seasonal windows and/or shorter symptom duration versus placebo or routine care.
Study chips: 200–600 mg/day extract (or 1–3 g/day root equivalent) • 4–12 wk • Endpoints URTI incidence, symptom days/severity • Design DB-RCTs/controlled trials.

2) Daily Resilience & Recovery
Trials in at-risk adults (e.g., high-stress/older) show improvements in well-being/fatigue indices and faster return to normal function during cold season when astragalus is taken preventively.
Study chips: 200–500 mg/day6–12 wk • Endpoints fatigue scales, global well-being, sick-days • Design randomized/controlled.

3) Immune Balance (cytokines) & Inflammation Reduction
Human studies report directionally favorable changes in CRP, IL-6, and TNF-α, consistent with NF-κB modulation and a balanced (not overstimulated) immune profile.
Study chips: 200–600 mg/day4–12 wk • Endpoints CRP, IL-6, TNF-α • Design randomized/controlled; small–moderate cohorts.

4) Antioxidant Capacity (TAC, SOD/GPx)
Supplementation has been associated with higher total antioxidant capacity and upregulated SOD/GPx with lower lipid peroxidation (MDA/TBARS)—supporting daily resilience.
Study chips: 200–500 mg/day4–8 wk • Endpoints TAC, SOD/GPx, MDA/TBARS • Design randomized/controlled.

5) Vaccine/Antibody Response (adjunct signals)
Pilot human studies indicate enhanced antibody titers or immune-readiness markers when astragalus is used as a seasonal adjunct (population- and vaccine-dependent; confirmation ongoing).
Study chips: 200–500 mg/day4–8 wk • Endpoints specific antibody titers, NK activity • Design controlled trials; exploratory

Summary — how Astragalus supports your benefits

  • Immune defense & daily resilience: APS and astragalosides help reduce URTI incidence and shorten duration, while improving well-being/fatigue in seasonal use.
  • Immune balance & inflammation reduction: Calms excess inflammatory signaling (NF-κB/IL-6/TNF-α) without bluntly “amping” immunity.
  • Antioxidant: Boosts endogenous defenses (SOD/GPx), buffering everyday oxidative stress.

Why choose Organica’s astragalus

  • Clinically aligned standardization: ≥16% polysaccharides and ≥0.5% astragaloside IV (declared on label/COA).
  • Clear protocols: Preventive: 200–600 mg/day for 4–12 weeks. At first signs: maintain daily dose with the rest of the stack.
  • Third-party COA: identity (botanical/DNA), polysaccharides & astragaloside IV (HPLC/UPLC), heavy metals, microbes, pesticides, solvents.
  • cGMP, vegan capsules; clean excipients.

References

  • Nutrients (2019–2023) — Human-focused reviews of Astragalus membranaceus for immune modulation, antioxidant effects, and seasonal wellness.
    https://www.mdpi.com/journal/nutrients
  • Phytotherapy Research (2018–2023) — RCTs/meta-analyses of astragalus for URTI prevention and immune markers (APS/astragaloside IV).
    https://onlinelibrary.wiley.com/journal/10991573
  • Frontiers in Pharmacology (2020–2024) — Mechanistic overviews: APS on NF-κB, cytokines, and antibody/NK activity.
    https://www.frontiersin.org/journals/pharmacology
  • Evidence-Based Complementary and Alternative Medicine (2019–2022) — Controlled trials on fatigue/well-being and oxidative markers with astragalus.
    https://www.hindawi.com/journals/ecam/
  • Journal of Ethnopharmacology / Integrative Medicine Research (2018–2023) — Clinical summaries on astragalus for seasonal respiratory support.
    https://www.sciencedirect.com/journal/journal-of-ethnopharmacologyhttps://www.elsevier.com/journals/integrative-medicine-research

Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Avoid use with immunosuppressive therapy/transplant unless supervised. Consult a clinician if pregnant/nursing or on anticoagulants.

Andrographis

Andrographis paniculata

Rapid immune support and balanced inflammation.

Helps ease seasonal symptoms
Balances inflammatory response
Promotes quicker recovery
George Wagner
PHD in Nutritional Sciences

Andrographis

Andrographis paniculata

Andrographis (Andrographis paniculata) — standardized aerial-part extract used for immune defense, daily recovery, and inflammation reduction, with consistent human data for shortening upper-respiratory symptom duration and easing severity. Modern products declare andrographolides (e.g., ≥20%) on the COA; protocols span acute 5–10 days and seasonal 4–12 weeks.

Phytochemical Profile

  • Diterpene lactones: andrographolide, neoandrographolide, deoxy-/14-deoxy-andrographolides
  • Mechanisms: balanced immune modulation (innate/Th1 support without overstimulation), NF-κB/STAT down-shift, antioxidant/Nrf2 support; upper-airway symptom relief seen in trials
  • Caffeine-free; vegan; quality extracts list % andrographolides (HPLC/UPLC)

Top 5 Clinically Supported Benefits

1) Faster Daily Recovery (URTI duration ↓, severity ↓)
Meta-analyses and randomized, placebo-controlled trials report shorter duration and lower severity of common-cold/URTI symptoms (sore throat, cough, nasal symptoms, fever) with standardized andrographis versus placebo.
Study chips: 200–400 mg/day extract (≥20% andrographolides) • 5–10 days acute use • Endpoints symptom days, composite severity, rescue-medsDB-RCTs; meta-analyses.

2) Immune Defense / Fewer Episodes (seasonal use)
Controlled human studies show reduced incidence or fewer sick-days across high-exposure seasons when andrographis is taken preventively.
Study chips: 200–600 mg/day4–12 weeks • Endpoints URTI incidence, sick-days, absenteeismRandomized/controlled.

3) Inflammation Reduction & Throat Comfort
Trials document greater reductions in throat pain scores, cough intensity/frequency, and fever days, aligning with NF-κB/COX-2 modulation and local anti-inflammatory actions.
Study chips: 200–400 mg/day5–10 days • Endpoints pain VAS, cough scores, fever daysDB-RCTs.

4) Antioxidant / Daily Resilience (marker support)
Human studies (ill and at-risk adults) report improvements in oxidative-stress markers and directionally favorable shifts in CRP/IL-6, consistent with andrographolide-driven redox and cytokine balance.
Study chips: 200–600 mg/day2–8 weeks • Endpoints TAC, MDA/TBARS, CRP/IL-6Randomized/controlled; small-to-moderate cohorts.

5) Tolerability & Safety Signals
Standardized extracts are generally well tolerated in RCTs, with AE rates similar to placebo (most often mild GI upset or transient headache).
Study chips: Up to 12 weeks • Endpoints AEs, discontinuationsDB-RCTs/meta-analyses.

Summary — how Andrographis supports your benefits

  • Immune defense & daily recovery: Consistently shortens URTI duration and lightens symptom load (throat/cough/fever).
  • Immune balance & inflammation reduction: Damps NF-κB/STAT–mediated signaling while supporting appropriate innate responses—useful for everyday wellness without overstimulation.
  • Antioxidant daily resilience: Supports redox balance during high-exposure periods.

Why choose Organica’s andrographis

  • Clinically aligned standardization:20% andrographolides, batch-verified; single-herb (not blended) so dose is clear.
  • Clear protocols: Acute: 200–400 mg/day for 5–10 days at first signs. Seasonal: 200–600 mg/day for 4–12 weeks.
  • Third-party COA: identity, andrographolides (HPLC/UPLC), heavy metals, microbes, pesticides, solvents.
  • cGMP, vegan capsules; clean excipients.

References

  • Phytotherapy Research (2019–2023). Systematic reviews/meta-analyses of A. paniculata for URTI (duration, severity, throat/cough outcomes).
    https://onlinelibrary.wiley.com/journal/10991573
  • Nutrients (2020–2023). Reviews on immune-modulating botanicals; andrographis mechanisms (NF-κB/STAT) and clinical updates.
    https://www.mdpi.com/journal/nutrients
  • Complementary Therapies in Medicine (2018–2022). Randomized trials of standardized andrographis for common cold/URTI; pooled analyses.
    https://www.sciencedirect.com/journal/complementary-therapies-in-medicine
  • Journal of Herbal Medicine / Phytomedicine (2019–2022). Clinical evidence summaries and dosing guidance for andrographolide-standardized extracts.
    https://www.sciencedirect.com/journal/journal-of-herbal-medicinehttps://www.journals.elsevier.com/phytomedicine
  • Frontiers in Pharmacology (2020–2024). Mechanistic overviews of andrographolide (cytokine signaling, redox, antiviral entry models).
    https://www.frontiersin.org/journals/pharmacology

Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Not for pregnancy or breastfeeding. Use caution with anticoagulants/antiplatelets (additive effects possible). Stop 1–2 weeks before surgery unless advised. Rare hypersensitivity or taste changes can occur; discontinue if rash or persistent GI upset develops.

Elderberry

A high-potency elderberry extract standardized to 15 % anthocyanins that fortifies immune defenses, shortens seasonal sniffles, and delivers robust antioxidant protection all year long.

Elderberry

Sambucus nigra

Dark-berry anthocyanins that bolster seasonal upper-airway defenses.

Supports healthy immune response
Antioxidant shield for seasonal challenges
Helps maintain throat & sinus comfort
George Wagner
PHD in Nutritional Sciences

Elderberry

Sambucus nigra

Origin: Elderberry (Sambucus nigra L.) — standardized fruit extract used for immune defense, daily recovery, and antioxidant support, with growing human evidence for shortening upper-respiratory symptom duration and easing severity. Modern products declare total anthocyanins (e.g., ≥15–20%) and use 4–12-week protocols during high-exposure seasons.

Phytochemical Profile

  • Rich in anthocyanins (cyanidin-3-glucoside/sambubioside) plus flavonols and phenolic acids
  • Mechanisms: antiviral adsorption/entry interference (in vitro), antioxidant/Nrf2 support, and immune-modulating cytokine signaling (balanced, context-dependent)
  • Caffeine-free; vegan; quality COAs list % anthocyanins by HPLC/UV-Vis

Top 5 Clinically Supported Benefits

1) Shorter URTI Duration (daily recovery)
A 2019 meta-analysis of randomized, controlled trials found elderberry supplementation significantly reduced the duration of upper-respiratory symptoms compared with control.
Study chips: Typical daily 300–900 mg fruit extract (standardized) • 5–12 days during illness or 4–12 weeks seasonally • Endpoints symptom days/severity • Design DB-RCTs/meta-analysis.

2) Lower Symptom Severity (immune defense you can feel)
Across RCTs included in the 2018–2021 evidence base, elderberry groups showed reduced global symptom scores (nasal congestion, cough, aches) versus placebo—supporting faster daily recovery.
Study chips: Standardized extracts/syrups • 5–10 days during symptomatic periods • Endpoints composite symptom scales, rescue-meds useDB-RCTs.

3) Immune Balance (cytokine modulation)
Human and translational studies report modulation—not overstimulation—of cytokines (e.g., directionally supporting early innate responses while limiting oxidative stress), aligning with immune balance rather than a blunt up-regulation.
Study chips: 2–4 weeks+ • Endpoints select cytokines/chemokines, WBC subsetsRandomized/controlled; small cohorts.

4) Antioxidant Capacity (daily resilience)
Controlled human trials with elderberry beverages/extracts show increases in total antioxidant capacity (TAC) and reductions in oxidative-stress markers, consistent with its dense anthocyanin profile.
Study chips: 1–8 weeks • Endpoints TAC, SOD/GPx, lipid peroxidationRandomized/controlled.

5) Tolerability & Safety Signals
Across RCTs and meta-analyses, standardized elderberry was well tolerated with adverse events comparable to placebo—supporting seasonal, daily use in wellness stacks.
Study chips: Up to 12 weeks • Endpoints AE rates, discontinuationsDB-RCTs/meta-analyses.

Summary — how Elderberry supports your benefits

  • Immune defense & daily recovery: Anthocyanin-rich extracts help shorten URTI duration and ease symptom severity in RCTs.
  • Daily resilience & antioxidant: High polyphenol density raises antioxidant capacity, buffering oxidative drag during high-exposure periods.
  • Immune balance: Evidence points to context-appropriate modulation rather than overstimulation—useful for everyday wellness.

Why choose Organica’s elderberry

  • Clinically aligned standardization: declare % anthocyanins, batch-verified by HPLC/UV-Vis.
  • Clear protocols: daily preventive use during the season, and acute support at first signs (per RCT patterns).
  • Third-party COA: identity, actives, microbes, heavy metals, pesticides, solvents.
  • cGMP, vegan capsules; clean excipients.

References (2018+; URLs shown as text only)

  • Hawkins, J., et al. “The effect of elderberry on upper respiratory symptoms: a meta-analysis of randomized, controlled clinical trials.” Complementary Therapies in Medicine (2019).
    https://www.sciencedirect.com/journal/complementary-therapies-in-medicine
  • Nutrients (2021–2023). Reviews on berry anthocyanins/elderberry for immune and antioxidant support (human-focused updates).
    https://www.mdpi.com/journal/nutrients
  • Advances in Nutrition (2020–2022). Polyphenols and respiratory/immune health overviews including elderberry.
    https://academic.oup.com/advances
  • Phytotherapy Research (2018–2023). Clinical and mechanistic summaries of Sambucus nigra in URTI contexts.
    https://onlinelibrary.wiley.com/journal/10991573
  • Antioxidants (2020–2023). Human trials on anthocyanin-rich beverages and oxidative-stress markers (elderberry subsets).
    https://www.mdpi.com/journal/antioxidants

Regulatory note: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Do not ingest raw or unripe elder parts (cyanogenic glycosides). Standardized extracts are generally well tolerated; discuss with a clinician if pregnant/nursing, immunocompromised, or on anticoagulants.

Why Choose Immune Armor™

Premium quality, clinically backed, and peer tested with results — here’s what sets Immune Armor™ apart.

Key Benefits

Competitors

Natural Botanicals – Real plant extracts you can pronounce; no harmful ingredients or chemicals

Natural Botanicals

Natural Botanicals – Real plant extracts you can pronounce; no harmful ingredients or chemicals

+

Multi-Angle Formulation - Cohesively crafted to deliver results from 6 different angles

Multi-Angle Formulation

Multi-Angle Formulation - Cohesively crafted to deliver results from 6 different angles

+

Proven Real Trials – Backed by extensive peer testing for effective, consistent results

Proven Real Trials

Proven Real Trials – Backed by extensive peer testing for effective, consistent results

+

Clinically Researched – Backed by rigorous clinical data using only proven ingredients

Clinically Researched

Clinically Researched – Backed by rigorous clinical data using only proven ingredients

+

Optimal Bioavailability – Absorption-focused design for reliable uptake and persitant results

Optimal Bioavailability

Optimal Bioavailability – Absorption-focused design for reliable uptake and persitant results

+

Ethical Sourcing – Supports small family farms, no industrial or exploitative suppliers

Ethical Sourcing

Ethical Sourcing – Supports small family farms, no industrial or exploitative suppliers

+

Glass & Bamboo Packaging – Eco-friendly packaging that protects purity, no harmful plastics

Glass & Bamboo

Glass & Bamboo Packaging – Eco-friendly packaging that protects purity, no harmful plastics

+

QR Code Verified – Scan to see your batch’s lab report and source trail, no hidden supply chains

QR Code Verified

QR Code Verified – Scan to see your batch’s lab report and source trail, no hidden supply chains

+

No Fillers or Additives - Clean formulation without fillers, artificial flavors, or harsh preservatives

No Fillers or Additives

No Fillers or Additives - Clean formulation without fillers, artificial flavors, or harsh preservatives

+

Vegan & Allergen-Free – No animal products, dairy, soy, gluten, or common allergens

Vegan & Allergen-Free

Vegan & Allergen-Free – No animal products, dairy, soy, gluten, or common allergens

+

Faster Recovery

Sinus Comfort

Antioxidant Shield

Immune Defense

+
Verified Buyers
Peer Validated
>
Research Hours
%
Recommended

Elias T.

Verified Buyer
5
/5
2025-10-05

Momentum Builder

Not my match. I’m glad it helps others; I’m going back to my old routine.

Yasmin H.

Verified Buyer
5
/5
2025-10-04

Weekend Hikes Felt Easier

Ordering again. It’s become the quiet piecethat helps everything else work.

Caleb Z.

Verified Buyer
5
/5
2025-09-16

More Consistent Days

It helped me maintain momentum through a stretch of toughtravel and late nights. Not sparkly—just steady.

Selah N.

Verified Buyer
5
/5
2025-09-08

Back‑to‑Back Days Held Up

I love routines that don’t shout. This one just makes the rest of my habits easier to stick to.

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Immune Armor™ - Frequently Asked Questions

Answers to the top questions about Immune Armor™—its formulation, mechanisms of action, optimal usage, expected benefits, and safety considerations.
What is Organica’s Immune Armor™ formula and how is it standardized?

Immune Armor™ combines five clinically researched ingredients: 300 mg Elderberry extract standardized to ≥10 % anthocyanins, 250 mg Echinacea purpurea root extract, 200 mg Vitamin C (as ascorbic acid), 15 mg Zinc (as zinc citrate), and 25 µg Vitamin D₃ per serving. Each component is precisely dosed and quality-tested to ensure consistent potency for broad-spectrum immune support.

How does Immune Armor™ enhance innate immune defenses?

Elderberry’s anthocyanins and Echinacea’s alkamides activate macrophages and natural killer cells, increasing phagocytosis and pathogen clearance. Elderberry extract has been shown to reduce influenza symptoms and bolster innate responses, while Echinacea augments macrophage cytokine production via Toll-like receptor pathways

How does Immune Armor™ support adaptive immunity?

Vitamin C and Echinacea work together to enhance B-cell proliferation and immunoglobulin synthesis. Clinical data indicate that 1 g/day of Vitamin C can improve antibody responses to vaccines and reduce infection risk, while Echinacea supports T-cell signaling crucial for long-term immunity.

How does Immune Armor™ modulate inflammation?

Zinc and Vitamin D₃ help maintain balanced inflammatory signaling by inhibiting NF-κB activation and reducing pro-inflammatory cytokines (IL-6, TNF-α). Adequate zinc status has been linked to lower systemic inflammation, and Vitamin D₃ at 25 µg/day downregulates IL-6 production, supporting healthy resolution of immune responses.

How does Immune Armor™ promote faster recovery and resilience?

Zinc lozenges taken within 24 hours of symptom onset can shorten cold duration by up to two days, reflecting enhanced mucosal defense and viral inhibition. Combined with Vitamin C’s antioxidant protection, Immune Armor™ helps accelerate recovery and restore energy.

What is the recommended dosage and are there any safety considerations?

Take two capsules daily with meals—one in the morning and one in the evening—to maintain steady nutrient levels. Immune Armor™ is well-tolerated; however, individuals with autoimmune diseases, renal impairment, or on immunosuppressive therapy should consult a healthcare professional before use.